Chelohart
Khavinson natural peptide complex (Cytomax) derived from heart tissue extract — used in Russian clinical practice for cardiovascular support and myocardial function restoration.
🔬 Mechanism of Action
Chelohart is a Khavinson Cytomax natural peptide complex derived from cardiac tissue using the standardized acidic extraction process that preserves bioactive short peptides below 10 kDa.
Chelohart's multi-peptide composition modulates: (1) contractile protein genes (alpha-MHC, cardiac troponin T) for maintained pump function, (2) mitochondrial biogenesis through PGC-1α and NRF-1 — critical because heart muscle depends on mitochondria for 95% of its ATP, (3) connexin-43 gap junction proteins that coordinate electrical coupling between cardiomyocytes, and (4) natriuretic peptide expression for fluid/electrolyte homeostasis.
In Khavinson's clinical studies, elderly patients receiving 10-day Chelohart courses showed improved echocardiographic parameters and reduced BNP markers at 3-month follow-up. Chelohart is the Cytomax form of the synthetic Cardiogen (AEDR).
Source: PMID: 15677927
📜Background & History
Chelohart is the cardiac Cytomax extract — natural counterpart to synthetic Cardiogen.
🎯 Research Use Cases
- ✓Heart health in aging
- ✓Cardiac function support
- ✓Cardiovascular protocols
💉 Dosing Protocol
| Typical Dose | 1-2 capsules/day |
| Frequency | 1-2× daily for 10-30 day cycles |
| Half-Life | ~30 minutes (estimated) |
⚠️Safety & Considerations
Standard Khavinson 10-30 day oral cycles. Capsule form — no injection or reconstitution required. Well tolerated.
⚡Interactions & Contraindications
Standard Cytomax capsule protocol.
🔗Synergies & Common Stacks
Chelohart (Cytomax extract) + Cardiogen (synthetic) = layered cardiac support.