Comparison
Sermorelin vs Tesamorelin
Side-by-side attributes from our library comparison data. Read each peptide leaf for dosing math, regulatory status, and citations.
Sermorelin vs. Tesamorelin
| Attribute | Sermorelin | Tesamorelin |
|---|---|---|
| FDA Status | Not FDA-approved (was revoked) | FDA-approved (Egrifta® - HIV lipodystrophy) |
| Half-Life | ~11–13 minutes | ~26 minutes (longer-acting) |
| Potency | Moderate GH stimulation | Stronger - more potent GHRH analog |
| Best For | General GH/IGF-1 anti-aging protocol | Visceral fat reduction (clinical + wellness) |
| WADA Status | Prohibited (S2) | Prohibited (S2) |
| Availability | Compounded pharmacy (Rx) | Branded Rx + compounded |
Verdict: Tesamorelin is the more potent and clinically validated GHRH analog with FDA approval for lipodystrophy. Sermorelin is more widely compounded and used for general anti-aging GH optimization at lower cost.