Weight Management

Amycretin

Novo amycretin · amycretin oral · amycretin injectable

Novo Nordisk investigational dual amylin and GLP-1 receptor agonist (amycretin), studied in oral and injectable obesity programs. Not CagriSema. Not a research-chem blend of cagrilintide plus semaglutide in one vial.

Not FDA-approved - research chemical
Reviewed by CalcMyPeptide Editorial Team
Last updated: September 2026Evidence: Emerging
Typical research dose
Investigational - sponsor protocol only
Frequency
Trial schedules only (oral and injectable programs)
Half-life
Program-dependent (oral vs injectable)
Common vials
N/A (oral)

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

  • Metabolic / weight6.5/10

    Dual amylin/GLP-1 is a serious obesity mechanism class. Haircut: no finished US label; oral and injectable programs are not the same product.

Compound card

Sequence
Dual amylin / GLP-1 agonist (Novo amycretin; oral and injectable programs)
Class
Investigational dual amylin and GLP-1 receptor agonist (Novo Nordisk)
Formula
Peptide co-agonist (proprietary Novo construct)
Status
Not FDA-approved · research use

How it works

Amycretin is Novo Nordisk’s investigational co-agonist at amylin and GLP-1 receptors, studied in both oral and injectable obesity programs. It is not CagriSema (cagrilintide + semaglutide as a fixed combination story), not standalone cagrilintide, and not semaglutide.

Source: Novo Nordisk pipeline disclosures; not a finished US label

Research Use Cases

  • Obesity pipeline literacy: Moderate
  • DIY reconstitution: Low

Dosing

PhaseDoseFrequencyNotes
Human careSponsor protocol onlyTrial scheduleOral vs injectable are different programs.
Research-chem SKUDo not inventn/aNo honest cake chart on this leaf.

Administration

Route / form
Oral or injectable under clinical protocol (program-specific)
Timing
Program-defined
Empty stomach?
No - Food timing is not critical.

Timeline

Trial programs
Satiety and weight endpoints are sponsor-owned. Not a community titration meme.

Who it is for

Obesity pipeline literacy

Moderate

Useful name to keep distinct from CagriSema.

DIY reconstitution

Low

Wrong tool.

Safety & Considerations

Investigational. Amylin-pathway and GLP-1-pathway GI effects are expected in class. Unverified vials are identity risk. Not pregnancy-safe by default.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

  • Not CagriSema. Not cagrilintide alone. Not semaglutide alone.
  • Oral and injectable amycretin programs are not interchangeable exposures.
  • Sponsor milligrams are not a gray-market protocol.
  • This site will not treat obesity from an investigational leaf.

Verdict

Amycretin is Novo’s dual amylin/GLP-1 program. It is not CagriSema and not a research blend you mix from two cakes. Identity first; no invented reconstitution math.

Interactions & Contraindications

Investigational. Amylin-pathway and GLP-1-pathway GI effects are expected in class. Unverified vials are identity risk. Not pregnancy-safe by default.

Frequently Asked Questions

Is amycretin the same as CagriSema?
No. CagriSema is the cagrilintide + semaglutide combination story. Amycretin is a single dual-agonist program.
Oral or injectable?
Novo has studied both. They are not the same exposure. Do not paste one program’s milligrams onto the other.

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