Anti-Aging

N-Acetyl Epitalon Amidate

NAEA · Ac-Epitalon-NH2 · acetylated amidated epitalon

N-acetylated, C-amidated AEDG (epitalon) — the same stability-cap trick as NASA on Semax. Dosage Peptide and others list a 5 mg longevity protocol. Dedicated analog papers are essentially absent. Parent epitalon/epithalamin literature (Khavinson) does not automatically transfer.

Not FDA-approved — research chemical
Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low1 peer-reviewed citation
Typical research dose
5-10 mg/day (vendor longevity protocols; analog-specific PK absent)
Frequency
1× daily for 10-20 day cycles (vendor)
Half-life
Not published for this analog
Common vials
10 mg / 50 mg
CAS
N/A
Molecular weight
Tetrapeptide analog
Dose it
10 mg + 2 mL BAC water5 mg/mL · 5000 mcg ≈ 100 units (U-100)
Open in calculator

Mechanism of Action

NAEA is AEDG (epitalon) with an N-acetyl cap and C-terminal amide — the same exopeptidase-evasion trick as NASA on Semax. Parent epitalon/epithalamin literature is Khavinson pineal-tetrapeptide work (PMID 12937225). This analog does not have its own human PK paper.

Source: Parent epitalon PMID: 12937225. NAEA: no indexed human PK as of 2026.

Analog, not a second epitalon trial

Vendor 5 mg “longevity protocols” are not citations. If you need evidence, read epitalon and treat this as uncharacterized.

Dosing Protocol

Typical Dose5-10 mg/day (vendor longevity protocols; analog-specific PK absent)
Frequency1× daily for 10-20 day cycles (vendor)
Half-LifeUnknown for this analog (parent epitalon PK is already thin)
Common Vial Sizes10 mg, 50 mg

Dosing Protocols

Vendor longevity SKU

Dose
5–10 mg/day
Frequency
10–20 day courses
Note: Inherited from epitalon practice. No analog trial.

Body-Weight Dosing Reference

Estimated doses extrapolated from the published research range of 500010000 mcg/day (referenced to 70 kg / 154 lb). These are approximations — consult a qualified healthcare provider for personalised guidance.

WeightLowTargetHigh
120 lb(54 kg)3857 mcg5786 mcg7714 mcg
140 lb(63 kg)4500 mcg6750 mcg9000 mcg
160 lb(73 kg)5214 mcg7821 mcg10429 mcg
180 lb(82 kg)5857 mcg8786 mcg11714 mcg
200 lb(91 kg)6500 mcg9750 mcg13000 mcg
220 lb(100 kg)7143 mcg10714 mcg14286 mcg
250 lb(113 kg)8071 mcg12107 mcg16143 mcg

💉 For exact syringe units based on your vial concentration, use the N-Acetyl Epitalon Amidate Reconstitution Calculator →

Administration

Route
Subcutaneous (typical research)
Timing
Evening in many vendor protocols — folklore.
Fasting Required?
No — food timing not critical

Expected Timeline

Unknown for analog
Do not copy telomere marketing onto NAEA.

Who Is It For?

Longevity analog SKU

Low

High catalog presence, near-zero analog papers.

Reconstitution Example

Vial
10 mg
Diluent
2 mL
Concentration
5 mg/mL
Per Unit (100u syringe)
50 mcg
Dose of 5000 mcg = 100 units on a 100-unit insulin syringe

Safety & Considerations

Research analog. Parent claims (telomerase, pineal) are already contested. Analog does not make them stronger. Not a drug.

Regulatory & Legal Status

FDA Status (US)
Research Only

Stability analog of epitalon. No analog-specific human PK or approval

WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

N-Acetyl Epitalon Amidate vs. Epitalon

AttributeN-Acetyl Epitalon AmidateEpitalon
StructureN-acetyl + C-amide AEDGParent AEDG tetrapeptide
Human PKNone for this analogThin even for the parent
SKUNAEA / 5 mg vendor protocolsStandard epitalon vial

Verdict: Same cap trick as NASA. Parent papers stay on epitalon. Analog claims are chemistry inference.

Dosing Quick Reference

N-Acetyl Epitalon Amidate— Dosing Guide
Dose Range
5-10 mg/day (vendor longevity protocols; analog-specific PK absent)
Half-Life
Unknown for this analog (parent epitalon PK is already thin)
Frequency
1× daily for 10-20 day cycles (vendor)
Route
Subcutaneous
10 mg vial50 mg vial
💧 2 mL BAC water📐 5 mg/mL💉 50 mcg/unit (100u syringe)
Anti-Agingcalcmypeptide.com

Frequently Asked Questions

Is this stronger than epitalon?
Unknown. Caps can slow breakdown. That is not a potency trial.
Same as epithalamin?
No. Epithalamin is a pineal extract. Epitalon is AEDG. NAEA is capped AEDG.

References

  1. Khavinson V et al. Epitalon parent literature.” Biogerontology / related (2003). PMID: 12937225

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