Weight Management

Petrelintide

ZP8396 · Zealand petrelintide

Zealand Pharma investigational long-acting amylin receptor agonist (petrelintide / ZP8396). Not pramlintide. Not cagrilintide. Not a research vial that inherits Symlin labeling.

Not FDA-approved - research chemical
Reviewed by CalcMyPeptide Editorial Team
Last updated: September 2026Evidence: Emerging
Typical research dose
Investigational - sponsor protocol only
Frequency
Trial schedules only
Half-life
Long-acting program (sponsor PK)
Common vials
N/A (oral)

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

  • Metabolic / weight5.5/10

    Amylin-pathway obesity programs are real. Haircut: investigational, not pramlintide label, not a DIY cake.

Compound card

Sequence
Long-acting amylin agonist (ZP8396 / petrelintide)
Class
Investigational long-acting amylin receptor agonist (Zealand Pharma)
Formula
Amylin analog (proprietary)
Status
Not FDA-approved · research use

How it works

Petrelintide (ZP8396) is Zealand Pharma’s investigational long-acting amylin receptor agonist. It sits in the amylin satiety class with pramlintide and cagrilintide, but it is not Symlin and not cagrilintide.

Source: Zealand Pharma clinical program disclosures; not a finished US label

Research Use Cases

  • Amylin pipeline literacy: Moderate
  • DIY reconstitution: Low

Dosing

PhaseDoseFrequencyNotes
Human careSponsor protocol onlyTrial scheduleNot Symlin pen math.
Research-chem SKUDo not inventn/aIdentity first.

Administration

Route / form
Parenteral under clinical protocol
Timing
Program-defined
Empty stomach?
No - Food timing is not critical.

Timeline

Trial programs
Satiety endpoints are sponsor-owned.

Who it is for

Amylin pipeline literacy

Moderate

Keep it distinct from GLP-1-only drugs.

DIY reconstitution

Low

Wrong tool.

Safety & Considerations

Investigational. Amylin-class nausea risk. Hypoglycemia risk rises when stacked carelessly with insulin — that is clinical pharmacology, not a gray-vial excuse. Unverified identity risk on research SKUs.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

  • Not interchangeable with pramlintide (Symlin) or cagrilintide.
  • Sponsor milligrams are not a research-chem table.
  • This site will not treat obesity or diabetes from this leaf.

Verdict

Petrelintide is Zealand’s long-acting amylin agonist. Not pramlintide. Not cagrilintide. Not a research cake with a Symlin insert.

Interactions & Contraindications

Investigational. Amylin-class nausea risk. Hypoglycemia risk rises when stacked carelessly with insulin — that is clinical pharmacology, not a gray-vial excuse. Unverified identity risk on research SKUs.

Frequently Asked Questions

Is petrelintide the same as cagrilintide?
No. Both are amylin-pathway agonists. Different sponsors and constructs.
Is it Symlin?
No. Symlin is pramlintide. Different molecule and label.

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