Peptide Stack

Wolverine Stack

BPC-157 + TB-500 · Wolverine blend · BPC/TB stack

Named research blend of BPC-157 plus TB-500 — the default two-peptide healing stack. We already have a full guide and GLOW/KLOW (which add GHK-Cu ± KPV). This leaf is the blend SKU itself. Each component is research-only; BPC-157 is FDA Category 2. No combined clinical trial.

Not FDA-approved — research chemicalWADA (S0) — prohibited in sport at all times
Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low2 peer-reviewed citations
Typical research dose
BPC-157 250-500 mcg/day · TB-500 2-5 mg twice weekly
Frequency
Daily (BPC-157) · 2× weekly (TB-500)
Half-life
Component-wise (BPC minutes IV; TB-500 hours)
Common vials
10 mg
CAS
N/A (blend)
Molecular weight
Multi-component
Dose it
10 mg + 2 mL BAC water → 5 mg/mL · 250 mcg ≈ 5 units (U-100)
Open in calculator

Mechanism of Action

Wolverine is BPC-157 + TB-500 in one named stack. BPC-157 is a 15-aa gastric peptide with extensive animal repair literature and no Phase 3. TB-500 is a thymosin β-4 fragment studied for actin/cell migration. GLOW adds GHK-Cu; KLOW adds KPV. There is no combined RCT.

Source: PMID: 29936067 (BPC-157), PMID: 20435714 (Tβ4/TB-500); see also /blog/wolverine-stack-peptide-guide

Dosing Protocol

Typical DoseBPC-157 250-500 mcg/day · TB-500 2-5 mg twice weekly
FrequencyDaily (BPC-157) · 2× weekly (TB-500)
Half-LifeMinutes (BPC IV PK) / ~2 hours (TB-500 metabolites longer)
Common Vial Sizes10 mg

Dosing Protocols

Component-wise (not a single INN)

Dose
BPC-157 250–500 mcg/day + TB-500 2–5 mg 2×/week
Frequency
See components
Note: Pre-blended vials need the blend calculator so the rate-limiting peptide is not overdrawn.

Administration

Route
Subcutaneous
Timing
BPC often daily; TB-500 twice weekly. Can be separate vials or one blend.
Fasting Required?
No — food timing not critical

Expected Timeline

Weeks 1–4
Community reports of pain/inflammation change; not a trial endpoint.

Who Is It For?

Recovery stack

Low

Two research peptides. BPC-157 is FDA Category 2. This is a name, not a drug.

Reconstitution Example

Vial
10 mg
Diluent
2 mL
Concentration
5 mg/mL
Per Unit (100u syringe)
50 mcg
Dose of 250 mcg = 5 units on a 100-unit insulin syringe
🧮 Calculate Your Exact Wolverine Stack Dose →

Safety & Considerations

Research blend. Angiogenic theoretical risk in active cancer. Sterile technique. See the Wolverine guide for reconstitution walkthroughs.

Regulatory & Legal Status

FDA Status (US)
Research Only

BPC-157 is FDA Category 2. TB-500 is research-only. Combination is not an approved product

WADA Status (2026)
Prohibited (S0)

Competitive athletes subject to anti-doping controls should not use Wolverine Stack.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Wolverine Stack vs. GLOW Stack

AttributeWolverine StackGLOW Stack
ComponentsBPC-157 + TB-500GHK-Cu + BPC-157 + TB-500
JobTwo-peptide recoveryRecovery plus copper-peptide skin/ECM
EvidenceComponent preclinical; no blend RCTSame — community blend
PIPUsually milder (no GHK-Cu)GHK-Cu sting is the rate limiter

Verdict: Wolverine is the two-peptide core. GLOW adds GHK-Cu. KLOW adds KPV on top of GLOW. Ingredient count is not evidence quality.

Dosing Quick Reference

Wolverine Stack— Dosing Guide
Dose Range
BPC-157 250-500 mcg/day · TB-500 2-5 mg twice weekly
Half-Life
Minutes (BPC IV PK) / ~2 hours (TB-500 metabolites longer)
Frequency
Daily (BPC-157) · 2× weekly (TB-500)
Route
Subcutaneous
10 mg vial
💧 2 mL BAC water📐 5 mg/mL💉 50 mcg/unit (100u syringe)
Peptide Stackcalcmypeptide.com

Frequently Asked Questions

Wolverine vs GLOW vs KLOW?▼
Wolverine = BPC + TB-500. GLOW adds GHK-Cu. KLOW adds KPV. Escalating ingredient lists, not escalating evidence.
Can I mix both in one syringe?▼
Community practice is yes for reconstitution compatibility. Dose control is easier as separate vials. Use the Blend/Stack calculator for a pre-mix.

References

  1. Sikiric et al. “BPC-157 reviews.” Various (2018). PMID: 29936067
  2. Goldstein / Tβ4 literature “Thymosin beta-4 / TB-500 actin literature.” Various (2010). PMID: 20435714

📚 Related Articles

What Is the Wolverine Stack? BPC-157 + TB-500 Dosing, Reconstitution & Calculator Guide
12 min read • Recovery
The Wolverine Stack: BPC-157 & TB-500 for Accelerated Recovery — Full Protocol
13 min read • Recovery

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