Cognitive & Nootropic

Adamax

Adamantane-Semax · Adamantyl-Semax

Adamantane-modified Semax analog sold as a nasal research spray. Search volume is real; dedicated papers are essentially absent. Treat every half-life and dose number as vendor folklore unless a citation appears. Parent Semax evidence does not automatically transfer to an adamantyl conjugate.

Not FDA-approved — research chemical
Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low1 peer-reviewed citation
Typical research dose
200-600 mcg/day (intranasal; vendor protocols only)
Frequency
1-2× daily (intranasal)
Half-life
Unknown
Common vials
5 mg / 10 mg
CAS
N/A
Molecular weight
Unverified per lot
Dose it
5 mg + 5 mL BAC water1 mg/mL · 200 mcg ≈ 20 units (U-100)
Open in calculator

Mechanism of Action

Adamax is marketed as adamantane-conjugated Semax. Adamantane is a real lipophilicity/stability trick in medicinal chemistry. Transferring Semax’s BDNF papers onto this conjugate without PK is a category error.

We list it because people search it and vendors sell it. Half-life on this page is explicitly unknown.

Source: Parent Semax PMID: 17430556. Adamax: no indexed human PK as of 2026.

No published human PK

Dose and duration numbers on vendor pages are not citations. If you need evidence, read Semax and treat this as an uncharacterized analog.

Dosing Protocol

Typical Dose200-600 mcg/day (intranasal; vendor protocols only)
Frequency1-2× daily (intranasal)
Half-LifeUnknown (no published human PK)
Common Vial Sizes5 mg, 10 mg

Dosing Protocols

Vendor nasal range only

Dose
200–600 mcg/day
Frequency
1–2× daily
Note: Folklore until a paper exists.

Administration

Route
Intranasal
Timing
As sold. Not a label.
Fasting Required?
No — food timing not critical

Expected Timeline

Unknown
Do not invent a Semax-like 15-minute onset as fact.

Who Is It For?

Nootropic analog SKU

Low

High search, near-zero papers. Listed for identity and recon, not endorsement.

Reconstitution Example

Vial
5 mg
Diluent
5 mL
Concentration
1 mg/mL
Per Unit (100u syringe)
10 mcg
Dose of 200 mcg = 20 units on a 100-unit insulin syringe

Safety & Considerations

Unknown human safety file. Nasal irritation possible. Adamantane moieties have their own CNS/renal baggage in other drugs — not characterized here.

Regulatory & Legal Status

FDA Status (US)
Research Only

Adamantane-Semax analog. No indexed human PK or approval

WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Adamax vs. Semax

AttributeAdamaxSemax
StructureAdamantane-Semax (vendor)ACTH 4–10 heptapeptide
Human PKNone indexedRussian clinical literature
Evidence levelLowLow–moderate (parent drug in Russia)

Verdict: Adamax is a search term and a SKU. Semax is the molecule with papers. Do not copy Semax onset onto Adamax.

Dosing Quick Reference

Adamax— Dosing Guide
Dose Range
200-600 mcg/day (intranasal; vendor protocols only)
Half-Life
Unknown (no published human PK)
Frequency
1-2× daily (intranasal)
Route
Subcutaneous
5 mg vial10 mg vial
💧 5 mL BAC water📐 1 mg/mL💉 10 mcg/unit (100u syringe)
Cognitive & Nootropiccalcmypeptide.com

Frequently Asked Questions

Does Adamax last longer than Semax?
That is the sales pitch. It is not a published human half-life.

References

  1. Ashmarin / Myasoedov lineage Semax parent literature (not Adamax).” Neuroscience literature (2007). PMID: 17430556

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