CalcMyPeptide
Khavinson BioregulatorAlso known as: Prostate Extract Bioregulator, Prostate Cytomax

Libidon

Libidon is a critical Cytomax natural bioregulator extracted from youthful prostate tissue, recognized as a non-negotiable cornerstone of extreme male longevity protocols. It offers a profound, epigenetic solution to the inevitable age-related decline of male reproductive health. It is aggressively prescribed to halt the brutal progression of Benign Prostatic Hyperplasia (BPH), radically support urinary function, and comprehensively restore underlying prostatic vitality without disrupting systemic testosterone levels.

Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low1 peer-reviewed citation

Quick Stats

Half-LifeMixture (variable)
Dose Range1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Vial SizesN/A (oral)
BioavailabilityOral capsules
Year Developed1980s

Scientific Data

Molecular Formula
Polypeptide extract (Prostate tissue <10 kDa)
Molecular Weight
Mixture (<10 kDa)
PubChem ID

Mechanism of Action

Libidon (A-16) is a Cytomax natural polypeptide extract from the prostate gland of young male calves, targeting the human prostate to restore normal cellular function and tissue architecture through epigenetic gene regulation. The prostate is uniquely vulnerable to aging: BPH (benign prostatic hyperplasia) affects ~50% of men by age 60 and ~90% by age 85, while prostate inflammation (prostatitis) is estimated to affect 8–16% of men at any given time. Both conditions involve a common core pathology — dysregulation of prostate epithelial cell proliferation, inflammation signaling (NF-κB, COX-2), and DHT (dihydrotestosterone) receptor sensitivity.

Libidon delivers short peptide signals from bovine prostate tissue (<10 kDa) that enter prostate cell nuclei to reactivate age-suppressed genes governing: cell cycle regulation (p53, PCNA), anti-inflammatory cytokine balance (IL-10 upregulation, IL-6 downregulation), and proper epithelial differentiation. Critically, Libidon does not manipulate DHT or testosterone — it works downstream, at the level of cellular gene expression, to restore what a healthy prostate cell would naturally produce.

In Khavinson's Russian clinical trials, courses of prostate polypeptide bioregulators showed statistically significant improvement in BPH symptom scores (IPSS), reduced PSA variability, and better urinary flow rates. The protocol typically combines Libidon (A-16) with Pielotax (A-9, kidney) — since BPH-induced urinary obstruction has direct upstream effects on renal function.

Source: PMID: 15677927

Background & History

Libidon is the prostate Cytomax extract, supporting prostatic glandular function.

Research Use Cases

  • Prostate health
  • BPH management support
  • Male reproductive aging

Dosing Protocol

Typical Dose1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Half-Life~30 minutes (estimated)

Dosing Protocols

Mini-Course / General Preventive (1 box)

Dose
2 capsules (20 mg)
Frequency
Once daily for 10 days, 30 min before meals
Note: Standard Khavinson mini-course (20 caps). Repeat every 6 months from age 40. Combine with Pielotax (A-9) for full urological system protection.

Full Monthly Course (BPH / Prostatitis)

Dose
2 capsules (20 mg)
Frequency
Twice daily for 30 days (120 caps = 2× 60-cap boxes)
Note: For active BPH symptoms or chronic prostatitis. Bi-annual 30-day courses. Core male urological stack: Libidon (A-16) + Pielotax (A-9) + Testoluten (A-13) for comprehensive male reproductive-urological protocol.

Intensive / Prostate Restoration Protocol

Dose
2 capsules (20 mg)
Frequency
Twice daily, repeated monthly as needed
Note: For advanced BPH, recurrent prostatitis, or post-procedure recovery. Physician supervision required. Not a replacement for medical evaluation of PSA elevation. Max: 4 caps/day (40 mg).

Administration

Route
Oral capsules (20-cap and 60-cap boxes)
Timing
30 minutes before meals. Morning + evening for intensive courses.
Fasting Required?
Yes — inject on an empty stomach

Expected Timeline

Days 1—30
Prostate epithelial gene expression restoration initiated. Early reduction in urinary urgency frequency reported in clinical populations.
Month 1–3
Improved urinary flow parameters. Reduced IPSS (International Prostate Symptom Score) in studied populations.
Month 3–6
Sustained reduction in prostate inflammatory tone. Improved tissue differentiation markers.

Who Is It For?

BPH / Prostate Health (Ages 50+)

Low

Prostate-specific bioregulator targeting cellular gene expression rather than hormonal pathways. Clinical data from Russian gerontological trials shows IPSS and flow rate improvements.

Preventive Male Health Protocol (Ages 40+)

Low

Recommended from age 40 as part of the Khavinson male biological age management stack alongside Testoluten (A-13) and Pielotax (A-9).

Safety & Considerations

Natural glandular extract (Cytomax) from bovine prostate tissue, <10 kDa. No testosterone or DHT. Does not affect PSA in the same way pharmaceutical interventions do. Meets European/Russian veterinary standards. Generally recognized as safe.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Interactions & Contraindications

Consult urologist if existing prostate conditions.

Dosing Quick Reference

Libidon— Dosing Guide
Dose Range
1-2 capsules/day
Half-Life
~30 minutes (estimated)
Frequency
1-2× daily for 10-30 day cycles
Route
Oral
Khavinson Bioregulatorcalcmypeptide.com

Frequently Asked Questions

Is Libidon hormonal?
No. Libidon is filtered to <10 kDa — completely free of testosterone, DHT, or estrogen. It delivers gene-regulatory signals to prostate cells to restore their own healthy function, not hormone supplementation.
Can I take Libidon with my BPH medication?
Libidon has no known interactions with alpha-blockers (tamsulosin) or 5-alpha reductase inhibitors (finasteride). Many practitioners use Libidon as a complementary restorative protocol alongside conventional BPH management. Always disclose all supplements to your physician.

References

  1. Khavinson VKh "Peptide bioregulators — a new class of geroprotectors".” Bulletin of Experimental Biology and Medicine (2002). PMID: 12677266

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Recommended SourceOral Bioregulator

Get Libidon from Vita-Stream — the comprehensive distributor for authentic Khavinson bioregulators. Oral capsules, no injections required.

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