N-Acetyl Semax Amidate
NASA · NA-Semax Amidate · Ac-Semax-NH2 · N-acetyl Semax amide
N-terminal acetylated, C-terminal amidated Semax. The caps are the same stability trick as N-acetyl Selank amidate. Flagship nasal SKU in the research-chem Semax family. Human PK for this analog is not published — dosing and half-life claims are inferred from parent Semax (ACTH 4–10 analog) plus analog chemistry.
Mechanism of Action
NASA is Semax with an N-acetyl cap and a C-terminal amide — the same stability edits used on N-acetyl Selank amidate. Parent Semax is an ACTH 4–10 analog with Russian clinical literature (BDNF/NGF, stroke/cognitive use).
This analog does not have its own human PK paper. Half-life and “stronger/longer” claims are chemistry inference plus vendor copy. Dose ranges below are community nasal SKUs, not a label.
Source: Parent Semax PMID: 17430556. Analog: no dedicated human PK paper.
Dosing Protocol
| Typical Dose | 250-750 mcg/day (intranasal) |
| Frequency | 1-2× daily (intranasal) |
| Half-Life | Longer than Semax (estimated; analog PK unpublished) |
| Common Vial Sizes | 5 mg, 10 mg |
Dosing Protocols
Intranasal (vendor range)
Body-Weight Dosing Reference
Estimated doses extrapolated from the published research range of 250–750 mcg/day (referenced to 70 kg / 154 lb). These are approximations — consult a qualified healthcare provider for personalised guidance.
| Weight | Low Dose | Target Dose | High Dose |
|---|---|---|---|
| 120 lb(54 kg) | 193 mcg | 386 mcg | 579 mcg |
| 140 lb(63 kg) | 225 mcg | 450 mcg | 675 mcg |
| 160 lb(73 kg) | 261 mcg | 521 mcg | 782 mcg |
| 180 lb(82 kg) | 293 mcg | 586 mcg | 879 mcg |
| 200 lb(91 kg) | 325 mcg | 650 mcg | 975 mcg |
| 220 lb(100 kg) | 357 mcg | 714 mcg | 1071 mcg |
| 250 lb(113 kg) | 404 mcg | 807 mcg | 1211 mcg |
💉 For exact syringe units based on your vial concentration, use the N-Acetyl Semax Amidate Reconstitution Calculator →
Administration
Expected Timeline
Who Is It For?
Cognitive / nootropic research
LowHigh search, thin analog data. Prefer parent Semax papers over NASA marketing.
Reconstitution Example
Safety & Considerations
Research analog. Nasal irritation possible. Not a substitute for diagnosed stroke or ADHD care. Do not confuse with N-acetyl Selank amidate (different peptide; NASA is Semax).
Regulatory & Legal Status
Analog of Semax (Russian ACTH 4–10 drug). This amidated form has no FDA/EMA approval
Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.
Research Chemical
US Compounding: Not eligible / not available
⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.
N-Acetyl Semax Amidate vs. Semax
| Attribute | N-Acetyl Semax Amidate | Semax |
|---|---|---|
| Structure | N-acetyl + C-amide Semax (NASA) | Parent ACTH 4–10 heptapeptide |
| Human PK | Not published for this analog | Russian clinical literature exists |
| Typical SKU | Nasal research spray | Nasal (including Russian drug product) |
| Evidence | Low — chemistry inference | Parent papers (e.g. PMID 17430556) |
Verdict: NASA is a stability analog. Semax is the molecule with papers. Do not treat vendor “longer/stronger” copy as PK.
Dosing Quick Reference
Frequently Asked Questions
Is NASA the Selank analog?▼
Is this more studied than Semax?▼
References
- Ashmarin / Myasoedov lineage “Semax (parent ACTH 4–10 analog).” Neuroscience / Russian clinical literature (2007). PMID: 17430556
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