CalcMyPeptide
Khavinson BioregulatorAlso known as: Liver & GI Extract Bioregulator, Hepatic Cytomax

Ovagen

Ovagen is a deeply restorative Cytomax bioregulator utilizing precise peptide fractions painstakingly extracted from youthful liver and gastrointestinal tissue. Serving as the natural powerhouse counterpart to Livagen, it is universally prescribed in elite detoxification protocols. It acts to rapidly reverse severe hepatotoxicity from heavy chemical exposure (or performance enhancement), forcefully normalize deep digestive function, and physically regenerate a damaged hepatic matrix.

Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low

Quick Stats

Half-LifeShort (tetrapeptide)
Dose Range1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Vial SizesN/A (oral)
BioavailabilitySublingual or subcutaneous injection
Year Developed1990s

Scientific Data

Molecular Formula
C20H32N4O9
Molecular Weight
472.50 g/mol
CAS Number
PubChem ID

Mechanism of Action

Ovagen (Leu-Glu-Asp-Pro) is a synthetic tetrapeptide bioregulator targeting the liver and gastrointestinal tract. By binding to specific DNA promoter regions, Ovagen normalizes gene transcription in hepatocytes, sharply reducing hepatocyte apoptosis during toxic challenge (like alcohol, viral hepatitis, or drug toxicity) and accelerating liver tissue regeneration.

It serves as a fast-acting synthetic counterpart to Sveitinorm (liver extract) and acts cooperatively with Livagen (which targets chromatin relaxation).

Source: PMID: 15677927

Background & History

Ovagen is the liver/GI Cytomax extract, supporting hepatic and digestive function.

Research Use Cases

  • Liver/GI health
  • Digestive function
  • Hepatoprotection

Dosing Protocol

Typical Dose1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Half-Life~30 minutes (estimated)

Dosing Protocols

Khavinson Protocol

Dose
10 - 20 mg
Frequency
Daily SubQ for 10 days, 1-2x per year
Note: Liver/GI bioregulator. Highly effective post-toxic exposure.

Administration

Route
Sublingual tablets or subcutaneous injection
Timing
Morning.
Fasting Required?
No — food timing not critical

Expected Timeline

Day 1-10 (course)
Hepatocyte gene expression restoration and anti-apoptotic signaling initiated.

Who Is It For?

Liver Defense / GI Health

Low

Liver bioregulator. Enhances liver regeneration capacity.

Safety & Considerations

Research peptide. Extensively used in Russian clinical protocols. Excellent safety profile.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Interactions & Contraindications

Standard Cytomax capsule protocol.

Synergies & Common Stacks

Ovagen (liver + GI) + Svetinorm (liver only) provide overlapping but complementary hepatoprotective support.

Dosing Quick Reference

Ovagen— Dosing Guide
Dose Range
1-2 capsules/day
Half-Life
~30 minutes (estimated)
Frequency
1-2× daily for 10-30 day cycles
Route
Oral
Khavinson Bioregulatorcalcmypeptide.com

Frequently Asked Questions

How does Ovagen differ from Svetinorm?
Ovagen is a targeted synthetic tetrapeptide providing a quick, powerful signaling burst. Svetinorm is a Cytomax extract providing broad-spectrum liver peptide maintenance. They are often used together.

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Recommended SourceOral Bioregulator

Get Ovagen from Vita-Stream — the comprehensive distributor for authentic Khavinson bioregulators. Oral capsules, no injections required.

Affiliate link · Full review