CalcMyPeptide
Khavinson BioregulatorAlso known as: Ala-Glu-Asp-Leu, AEDL, Bronchial Bioregulator

Bronchogen

Bronchogen (Ala-Glu-Asp-Leu) is an advanced Khavinson tetrapeptide bioregulator developed specifically for deep pulmonary restoration. Acting far beyond bronchodilators, it is prescribed in extensive regenerative protocols to physically rebuild damaged lung tissue. Highly effective at combating chronic obstructive pulmonary disease (COPD), severe asthma, and post-viral lung scarring by essentially rebooting local cellular defense mechanisms.

Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low1 peer-reviewed citation

Quick Stats

Half-LifeShort (tetrapeptide)
Dose Range10-20 mg/day (oral) or 1-2 mg SC
Frequency1× daily for 10-30 day cycles
Vial Sizes5 mg, 10 mg
BioavailabilitySublingual or subcutaneous injection
Year Developed1990s

Scientific Data

Molecular Formula
C19H32N6O10
Molecular Weight
504.50 g/mol
CAS Number
PubChem ID

Mechanism of Action

Bronchogen (Ala-Glu-Asp-Leu) is a synthetic tetrapeptide bioregulator targeting bronchial and pulmonary epithelium. It normalizes bronchial epithelial cell gene expression disrupted by chronic inflammation. It promotes mucociliary clearance, regulates secretory IgA production, and downregulates pro-inflammatory cytokines in the respiratory tract. Khavinson studies show improved lung function in patients with chronic bronchitis and COPD.

Source: PMID: 15677927

Background & History

Bronchogen (AEDL) targets bronchial epithelium for respiratory health.

Research Use Cases

  • COPD support
  • Chronic bronchitis
  • Respiratory mucosal repair

Dosing Protocol

Typical Dose10-20 mg/day (oral) or 1-2 mg SC
Frequency1× daily for 10-30 day cycles
Half-Life~30 minutes (estimated)
Common Vial Sizes5 mg, 10 mg

Dosing Protocols

Khavinson Protocol

Dose
10 - 20 mg
Frequency
Daily SubQ for 10 days, 1-2x per year
Note: Respiratory bioregulator course. Often combined with Chonluten or Taxorest.

Body-Weight Dosing Reference

Estimated doses extrapolated from the published research range of 100020000 mcg/day (referenced to 70 kg / 154 lb). These are approximations — consult a qualified healthcare provider for personalised guidance.

WeightLowTargetHigh
120 lb(54 kg)771 mcg8100 mcg15429 mcg
140 lb(63 kg)900 mcg9450 mcg18000 mcg
160 lb(73 kg)1043 mcg10950 mcg20857 mcg
180 lb(82 kg)1171 mcg12300 mcg23429 mcg
200 lb(91 kg)1300 mcg13650 mcg26000 mcg
220 lb(100 kg)1429 mcg15000 mcg28571 mcg
250 lb(113 kg)1614 mcg16950 mcg32286 mcg

💉 For exact syringe units based on your vial concentration, use the Bronchogen Reconstitution Calculator →

Administration

Route
Sublingual tablets or subcutaneous injection
Timing
Morning.
Fasting Required?
No — food timing not critical

Expected Timeline

Day 1-10 (course)
Bronchial epithelial gene expression restoration initiated.
Month 3-6
Improved respiratory function and reduced exacerbations with repeat courses.

Who Is It For?

Respiratory / Lung Health

Low

Bronchial bioregulator. Restores age-suppressed or inflammation-suppressed bronchial gene expression.

Reconstitution Example

Vial
5 mg
Water
2.5 mL
Concentration
2 mg/mL
Per Unit (100u syringe)
20 mcg
Dose of 1000 mcg = 50 units on a 100-unit insulin syringe

Safety & Considerations

Research peptide. Extensively used in Russian clinical protocols. Excellent safety profile.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Interactions & Contraindications

Standard Khavinson protocol.

Synergies & Common Stacks

Bronchogen (synthetic) + Taxorest (bronchial Cytomax) = layered respiratory support.

Bronchogen (bronchial epithelium) + Chonluten (alveolar/surfactant) = comprehensive lung bioregulator protocol.

Dosing Quick Reference

Bronchogen— Dosing Guide
Dose Range
10-20 mg/day (oral) or 1-2 mg SC
Half-Life
~30 minutes (estimated)
Frequency
1× daily for 10-30 day cycles
Route
Subcutaneous
5 mg vial10 mg vial
💧 2.5 mL BAC water📐 2 mg/mL concentration💉 20 mcg/unit (100u syringe)
Khavinson Bioregulatorcalcmypeptide.com

Frequently Asked Questions

What does Bronchogen target?
Bronchogen targets the bronchial epithelium. It normalizes mucin production, improves cilia function for airway clearance, and reduces local respiratory inflammation.

References

  1. Khavinson VKh et al. "Peptide bioregulators in the treatment of chronic bronchitis".” Advances in Gerontology (2004). PMID: 15570775

📚 Related Articles

Recommended SourceOral Bioregulator

Get Bronchogen from Vita-Stream — the comprehensive distributor for authentic Khavinson bioregulators. Oral capsules, no injections required.

Affiliate link · Full review