Khavinson BioregulatorTarget: LungsRespiratory

Taxorest

Bronchial Extract Bioregulator · Bronchial Cytomax · Таксорест

Taxorest is the Cytomax bronchial-mucosa complex on the official 21-SKU list. Bronchogen and Chonluten are the airway cytogens. Honluten is an extra lung-extract product in some catalogs - adjacent, not a 22nd silent Cytomax on the e-peptide poster.

Not FDA-approved - research chemical
Reviewed by CalcMyPeptide Editorial Team
Last updated: August 2026Evidence: Low4 peer-reviewed citations
Typical research dose
1-2 capsules/day
Frequency
1-2× daily for 10-30 day cycles
Half-life
Mixture (variable)
Common vials
N/A (oral)
CAS
N/A (biological extract)
Molecular weight
Mixture (<10 kDa)

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

  • Longevity / aging3.5/10

    Khavinson-school tissue peptide. Single-lab concentration after haircut. Not a Western Phase 3 geroprotector.

  • Immune3/10

    Respiratory aisle in the school. Not an asthma drug.

Compound card

Sequence
Bronchial mucosa peptide complex (mixture, not a single CAS)
Class
Khavinson Cytomax capsule complex (Bronchial mucosa)
Formula
Polypeptide extract (Bronchial tissue <10 kDa)
Status
Not FDA-approved · research use

How it works

Taxorest (A-19) is a Cytomax natural polypeptide extract from the bronchial mucosa of young calves, targeting human bronchial epithelial cells, Clara cells, and type II pneumocytes to restore age-silenced gene expression governing mucociliary clearance, surfactant synthesis, and bronchial anti-inflammatory signaling. The lungs undergo progressive structural aging: mucociliary clearance slows (reducing the ability to expel inhaled particles), alveolar surface area declines by 4 m² per decade after age 30, and type II pneumocyte reserve capacity for surfactant production diminishes, contributing to declining FEV1 and increased respiratory infection susceptibility.

Taxorest delivers short peptide signals (<10 kDa) from bovine bronchial tissue. These peptides penetrate bronchial cell nuclei to reactivate transcription of genes encoding: CFTR (cystic fibrosis transmembrane conductance regulator, critical for airway surface liquid homeostasis), MUC5AC and MUC5B (airway mucins essential for the gel-on-brush mucociliary defense system), surfactant protein D (SP-D, which neutralizes inhaled pathogens), and IL-10 (bronchial anti-inflammatory cytokine). This is a tissue restoration mechanism - not a bronchodilator or anti-inflammatory drug.

In Khavinson's protocols, Taxorest (A-19, bronchial) is often paired with Chelohart (A-14, heart) and Ventfort (A-3, blood vessels) for the cardiovascular-pulmonary system bundle, since pulmonary vascular resistance and gas exchange efficiency are directly coupled to cardiac output demands.

Source: PMID: 15677927

Khavinson map

Canonical 41
Class
Cytomax (natural peptide complex)
Organ
Bronchial mucosa
Target
Lungs
System
Respiratory
Sequence
Mixture / not a single CAS
Таксорест

Used in bioregulator stacks

Manufacturer-style organ combinations - not FDA protocols. Every name is a live leaf.

The Khavinson school

Vladimir Khatskelevich Khavinson (1946–2024) spent five decades at what became the St. Petersburg Institute of Bioregulation and Gerontology arguing a simple, stubborn idea: aging is, in part, a failure of tissue-specific peptide signals, and those signals can be restored. The first products were not “peptides” in the Instagram sense. They were Cytamins - polypeptide fractions isolated from a named organ of young animals. Later commercial refinements of those fractions are sold as Cytomaxes (Cytomed / NPCRIZ): still mixtures, still oral capsules, still defined by the source organ rather than a single sequence. When the group identified short active motifs inside those mixtures, they synthesized them as Cytogens - di-, tri-, and tetrapeptides with a one-letter code (KE, AEDG, KED, EDR, KEDP, and so on).

That three-layer stack is the whole map. Cytamin / pharmaceutical extracts (Thymalin, Epithalamin, Cortexin, Retinalamin, Prostatilen) are the clinic-era injectables registered in the former Soviet pharmacopeia. Cytomaxes are the capsule complexes Cytomed still lists as a 21-SKU organ line. Cytogens are the defined synthetics. English-language educators, including Brenden Henry’s public writing at Peptide Science Institute, add a further commercial distinction - later analog SKUs (N-acetyl, amidate, “V2” complexes) sold as more stable or more diverse than the original Cytomed lots. That last layer is a product taxonomy, not a Khavinson paper. We describe it so readers are not gaslit by three bottles with the same organ name. We do not reproduce paid Peptide Mastery protocols, Precision Cell Method language, or anyone else’s course IP.

Full Cytamin → Cytomax → Cytogen map, literature limits, and how we counted 41

The mechanism Khavinson published is epigenetic, not receptor-agonist in the GLP-1 sense. Short peptides are claimed to enter nuclei, interact with DNA/histones, and reopen tissue-specific transcription that condensed with age (heterochromatin → euchromatin). Reviews in the Bulletin of Experimental Biology and Medicine and Neuroendocrinology Letters (PMID 14523363, 15677927, 23888677) are the citable core. Complementary GI pharmacology is not mystical: di- and tripeptides are PEPT1/LAT substrates, which is why oral capsules are even a conversation. What is not established in Western Phase 3 programs is organ-by-organ disease treatment, telomere reversal as a clinical endpoint, or the manufacturer claim that Cytomax is “a third stronger” than Cytogen. Those are NPCRIZ marketing sentences.

Khavinson’s group published hundreds of papers, many in Russian, many in the same journal family. That is a real literature. It is also a literature with limited independent Western replication, small n, and a habit of using one review PMID as a stamp on every organ. On this site a leaf earns its organ story, its Cytomax↔Cytogen pair, its sequence if it has one, and an honest sentence about what has not been shown. Reconstitution math belongs on cytogens sold as vials. Cytomax capsules do not get a fake 5 mg vial.

The 41 we treat as canonical are the 21 Cytomaxes on the public e-peptide/Cytomed list, the 12 Cytogens on that same commercial line (including Vesilut, which Western catalogs often drop), plus eight historically load-bearing molecules that sit beside the capsule SKUs: Epitalon, Vilon, Thymogen, Livagen, Cortagen, Prostamax, Thymalin, and Epithalamin. Honluten, Cortexin, Retinalamin, Prostatilen, Thymulin, N-acetyl-epitalon-amidate, Pinalex, and the GPL Man / GPL Femme kits are covered as adjacent - same school or same storefront, not padded into a fake 41.

Public English-language teaching (including Brenden Henry at peptidescienceinstitute.com) is cited as context, not copied. Paid Peptide Mastery / Peptide Salvation text stays theirs.

History of this molecule

Airway peptide bioregulation splits mucosa (Taxorest) from lung parenchyma (Honluten in some lines) from bronchial synthetics (Bronchogen, Chonluten/EDG). The official Cytomed 21 includes Taxorest, not Honluten. We still cover Honluten because US vendors sell it.

This is not a LABA, not inhaled corticosteroid, not a CFTR modulator. Smoking-related disease still starts with cessation.

Caveats

Airway Cytomax is not a US dietary-supplement monograph and not a drug. The tissue-extract model means lot-to-lot composition is a fingerprint, not a single CAS number. English-language “V2” bottles that claim more peptide diversity are a later commercial layer (mass-spec marketing from specific brands) - they are not Khavinson’s 1990s papers. Animal-source capsules are inappropriate if the reader has a religious or allergy constraint on the source species. None of this replaces care for the actual organ disease.

Full 41-map: Khavinson bioregulators index · Bioregulator stacks

Research Use Cases

  • ✓Bronchial Cytomax vs Bronchogen
  • ✓Not a COPD treatment page

Dosing

PhaseDoseFrequencyNotes
Mini-Course / General Preventive (1 box)2 capsules (20 mg)Once daily for 10 days, 30 min before mealsStandard Khavinson mini-course (20 caps). Repeat every 6 months. For smokers or those with occupational exposure, combine with Chelohart (A-14) for the pulmonary-cardiac support bundle.
Full Monthly Course (COPD / Chronic Lung Support)2 capsules (20 mg)Twice daily for 30 days (120 caps = 2× 60-cap boxes)Bi-annual 30-day courses for adults with COPD stage I–II, chronic bronchitis, post-COVID lung recovery, or significant smoking history. Core pulmonary stack: Taxorest (A-19) + Chelohart (A-14) + Ventfort (A-3).
Intensive / Pulmonary Restoration Protocol2 capsules (20 mg)Twice daily, repeated monthlyPost-COVID long-haul respiratory recovery, active COPD management support (adjunct), or occupational dust/chemical exposure. Physician supervision required. Not a bronchodilator or replacement for inhaled therapy. Max: 4 caps/day (40 mg).

Administration

Route / form
Oral capsules - swallowed with water. Cytomed Cytomaxes ship as capsules, not sublingual tablets and not lyophilized research vials.
Timing
Morning, with water, about 30 minutes before meals (empty stomach).
Empty stomach?
Yes - Empty stomach - about 30 minutes before meals. Cytomed boxes sometimes print “with food” because they are labeled as supplements; the manufacturer user-guide preference is before meals for absorption.

Taxorest: Not a research vial vs Oral capsule

Not a research vial
Bioavailability
Not applicable. This Cytomax SKU is not sold as a lyophilized research vial. There is no SubQ F% because Cytomed does not ship this complex as a cake.
Dose note
Do not reconstitute Taxorest. No BAC-water chart, no 5 mg vial math, no units-on-a-U-100 conversion. The defined-sequence vial in this aisle is the cytogen pair (Bronchogen and Chonluten (airway cytogens)), a different SKU. There is no pharmaceutical-extract SKU that is this capsule in a syringe.
Advantages
  • The defined-sequence vial in this aisle is the cytogen pair (Bronchogen and Chonluten (airway cytogens)), a different SKU.
  • There is no pharmaceutical-extract SKU that is this capsule in a syringe.
  • Reconstitute Bronchogen or Chonluten if you bought those cytogens. Confirm the bottle: Taxorest capsule vs Chonluten (EDG) vs Honluten extract. One-letter collisions are a live search disaster.
Considerations
  • Taxorest is an oral capsule complex. It is not a 5 mg lyophilized research vial.
  • Inventing recon math for a zero-mg Cytomax vial is how people inject the wrong product.
  • Not an official Cytomed sublingual tablet, IM ampoule, or eye drop either.
Oral capsule
Bioavailability
Not quantified in a Western PK study. Official Cytomed form is a swallowed capsule. PEPT1/LAT transport is class biology for short peptides, not an F% for this tissue mixture.
Dose note
Typical Cytomed labeling: 1–2 capsules daily in 10–30 day courses, swallowed with water about 30 minutes before meals (empty stomach). Manufacturer protocol, not an FDA label. Some boxes print “with food” because they are labeled as supplements; the timing copy we use is before meals.
Advantages
  • Official form for Taxorest: swallow the capsule with water. No reconstitution step and no 5 mg cake.
  • Bronchial-mucosa Cytomax (Cytomed A-19) on the official 21. Honluten is a catalog lung SKU, not a 22nd silent Cytomax on the e-peptide poster.
  • Course-based (10–30 days, a few times a year in manufacturer folklore), not a daily forever drug.
Considerations
  • Bronchial mucosa Cytomax is a peptide mixture / lot fingerprint, not a single CAS. English “V2” bottles are a later commercial layer, not a Khavinson RCT.
  • Russian school literature is not an FDA organ-disease label.
  • Third-party lingual SKUs exist in the wild. We do not claim sublingual as the official Cytomed Cytomax form.
Recommendation: Swallow Taxorest as oral capsules with water, about 30 minutes before meals. Bronchial-mucosa Cytomax on the 21-SKU poster, not a research vial, not an inhaler steroid, and not Honluten. Pair: Bronchogen and Chonluten. Honluten is a separate catalog lung SKU. Keep the inhaler.

Timeline

Days 1 - 14
Bronchial epithelial gene expression restoration initiated. Early improvement in mucociliary clearance capacity.
Month 1–2
Reduced chronic cough frequency, improved bronchial secretion consistency, better morning respiratory quality.
Month 3–6
Sustained improvement in bronchial mucosal integrity. Reduced respiratory infection frequency.

Who it is for

Respiratory Aging / COPD Support

Low

Targets bronchial epithelial and Clara cell gene expression. Restores mucociliary clearance and surfactant production at the transcription level.

Post-COVID Lung Recovery

Low

Used in Russian longevity protocols for post-viral airway mucosal rehabilitation. Addresses the bronchial epithelial damage component of long COVID respiratory symptoms.

Safety & Considerations

Natural glandular extract (Cytomax) from bovine bronchial tissue, <10 kDa. No hormones. Meets European/Russian veterinary standards. Generally recognized as safe.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

  • Cytomax SKUs are oral capsules. Do not run SubQ reconstitution math on a zero-mg vial.
  • Lot-to-lot composition is a fingerprint, not one sequence.
  • This site will not treat the named organ disease from a peptide page.
  • English-language V2 / analog bottles are a later commercial layer, not a Khavinson RCT.

Verdict

Taxorest is a Cytomax capsule complex from Bronchial mucosa. It is not the paired cytogen, not a 5 mg research cake, and not a US supplement monograph. The organ story is in the dossier on this page.

Interactions & Contraindications

This site will not treat COPD from a peptide page.

Synergies & Common Stacks

Complex vs cytogen.

Frequently Asked Questions

Oral capsule or injection?▼
Taxorest is a Cytomax oral capsule: swallow with water, about 30 minutes before meals. It is not a 5 mg lyophilized research vial and not an official Cytomed sublingual tablet (third-party lingual SKUs exist in the wild). If you want a defined-sequence powder to reconstitute, that is the cytogen pair (Bronchogen / Chonluten), not this complex. Do not run BAC math on a capsule SKU. Honluten is a catalog lung SKU, not on the e-peptide 21. Chonluten is the cytogen (EDG).
Taxorest vs Honluten vs Bronchogen vs Chonluten?▼
Taxorest = bronchial-mucosa Cytomax (on the 21). Honluten = lung-extract SKU in some catalogs (not on the e-peptide 21). Bronchogen and Chonluten = airway cytogens.
Asthma drug?▼
No. Keep the inhaler.
COVID protocol?▼
Not a labeled antiviral. Do not file old blogs as evidence.
Reconstitution?▼
Not Taxorest. Cytogen vials if purchased as synthetics.
Is Taxorest a bronchodilator?▼
No. Taxorest does not dilate bronchial smooth muscle or affect airway resistance acutely. It works by restoring the gene expression of the bronchial epithelium - improving mucociliary clearance capacity, surfactant production, and bronchial anti-inflammatory signaling over the course of weeks to months.
Can Taxorest help after COVID-19?▼
Post-COVID respiratory symptoms often involve persistent bronchial epithelial dysfunction and reduced mucociliary clearance. Taxorest addresses these at the cellular gene expression level. It is used in Russian longevity medicine alongside Endoluten (A-8, immunity/circadian) and Vladonix (A-6, thymus) for post-viral recovery protocols.

References

  1. Khavinson VKh et al. “Tissue-specific effects of peptides.” Bulletin of Experimental Biology and Medicine (2005). PMID: 15677927
  2. Khavinson VKh, Lin’kova NS, Tarnovskaya SI “Short peptides regulate gene expression.” Bulletin of Experimental Biology and Medicine (2013). PMID: 23888677
  3. Khavinson VKh, Morozov VG “Peptide regulation of aging: from experimental studies to clinical practice.” Advances in Gerontology (2003). PMID: 14523363
  4. Khavinson VKh “"Peptide bioregulators - a new class of geroprotectors".” Bulletin of Experimental Biology and Medicine (2002). PMID: 12677266

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Get Taxorest from Vita-Stream - a distributor for Khavinson-line oral capsules. No reconstitution math on a Cytomax bottle.

Affiliate link · Full review