CalcMyPeptide
Khavinson BioregulatorAlso known as: Heart Extract Bioregulator, Cardiac Cytomax

Chelohart

Chelohart holds a prestigious position as a Cytomax bioregulator—a natural, deeply complex peptide fraction painstakingly extracted directly from the cardiac tissue of adolescent animals. Carrying the exact epigenetic sequencing required for heart function, it is heavily relied upon in traditional Russian clinical practice to reverse severe hypertrophy, halt cardiac arrhythmias, and systematically rebuild a failing myocardium at the cellular level.

Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low1 peer-reviewed citation

Quick Stats

Half-LifeMixture (variable)
Dose Range1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Vial SizesN/A (oral)
BioavailabilityOral capsules
Year Developed1980s

Scientific Data

Molecular Formula
Polypeptide extract (Myocardium tissue <10 kDa)
Molecular Weight
Mixture (<10 kDa)
PubChem ID

Mechanism of Action

Chelohart (A-14) is a Cytomax natural polypeptide extract from the cardiac muscle (myocardium) of young calves, delivering a broad-spectrum library of short peptide signals (<10 kDa) targeting human cardiomyocytes. The heart is the most metabolically active organ in the body — by age 60, cardiac output and cardiomyocyte regenerative capacity have measurably declined, leaving the heart more vulnerable to ischemia, oxidative damage, and arrhythmia.

Chelohart's peptides penetrate cardiomyocyte nuclei to relax age-silenced chromatin and reactivate transcription of proteins critical to heart muscle integrity: sarcomere proteins (actin, myosin), mitochondrial respiratory enzymes, and antioxidant defense genes (SOD, catalase). This distinguishes it sharply from simply "protecting" the heart with antioxidants — it works at the gene regulation level.

In the Khavinson system, Chelohart is the natural oral extract counterpart to Cardiogen (the synthesized tetrapeptide Ala-Glu-Asp-Arg). Khavinson's published research from the St. Petersburg Institute (2004) documents normalization of lipid metabolism, improved tolerance to physical load, and reduced cardiac stress markers in elderly patients following polypeptide bioregulator courses. The recommended companion is always Ventfort (A-3, blood vessel extract) to simultaneously support the vascular delivery system alongside the cardiac muscle.

Source: PMID: 15677927

Background & History

Chelohart is the cardiac Cytomax extract — natural counterpart to synthetic Cardiogen.

Research Use Cases

  • Heart health in aging
  • Cardiac function support
  • Cardiovascular protocols

Dosing Protocol

Typical Dose1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Half-Life~30 minutes (estimated)

Dosing Protocols

Mini-Course / General Preventive (1 box)

Dose
2 capsules (20 mg)
Frequency
Once daily for 10 days, 30 min before meals
Note: Standard Khavinson mini-course (1 pack / 20 caps). Repeat every 6 months. Always pair with Ventfort (A-3, vascular extract) — the heart and vessel health must be addressed together.

Full Monthly Course (ages 40–50)

Dose
2 capsules (20 mg)
Frequency
Twice daily for 30 days (120 caps = 2× 60-cap boxes)
Note: Bi-annual 30-day courses from age 40–45; 3 courses/year after 50. Core cardiovascular stack: Chelohart (A-14) + Ventfort (A-3) + Endoluten (A-8) for cardio-neuroendocrine support.

Intensive / Cardiac Support Protocol

Dose
2 capsules (20 mg)
Frequency
Twice daily, repeated monthly as needed
Note: For post-MI recovery, chronic heart failure support, or significant age-related cardiac decline. Physician supervision required. Consider adding Cardiogen (synthesized tetrapeptide) as an initial 10-day burst before transitioning to oral Chelohart maintenance. Max: 4 caps/day (40 mg).

Administration

Route
Oral capsules (20-cap and 60-cap boxes)
Timing
30 minutes before meals. Morning + evening for intensive courses.
Fasting Required?
Yes — inject on an empty stomach

Expected Timeline

Days 1–10 (mini-course)
Cardiomyocyte gene expression restoration initiated. Early users may notice reduced exertional fatigue.
Month 1–2
Improved cardiac stamina, normalized lipid metabolism markers in clinical populations.
Month 3–6
Sustained heart muscle integrity support. Reduced cardiac oxidative stress markers per Khavinson 2004 research data.

Who Is It For?

Cardiac Aging / Heart Muscle Health

Low

Broad-spectrum myocardial bioregulator targeting cardiomyocyte gene expression. Best for preventive maintenance and post-illness recovery.

Cardiovascular Longevity Protocol

Low

Essential component of the Khavinson cardiovascular stack alongside Ventfort (A-3). Addresses the cardiac muscle directly while Ventfort targets the vessel walls.

Safety & Considerations

Natural glandular extract (Cytomax) from bovine cardiac muscle, <10 kDa. No hormones. Meets strict European/Russian veterinary standards. Generally recognized as safe for long-term use.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Interactions & Contraindications

Standard Cytomax capsule protocol.

Synergies & Common Stacks

Chelohart (Cytomax extract) + Cardiogen (synthetic) = layered cardiac support.

Dosing Quick Reference

Chelohart— Dosing Guide
Dose Range
1-2 capsules/day
Half-Life
~30 minutes (estimated)
Frequency
1-2× daily for 10-30 day cycles
Route
Oral
Khavinson Bioregulatorcalcmypeptide.com

Frequently Asked Questions

Should I take Chelohart or Cardiogen?
They complement each other. Cardiogen is a synthesized tetrapeptide providing a fast, precise signal for cardiac gene activation — ideal for a short 10-day intervention. Chelohart is the natural broad-spectrum extract providing sustained maintenance over 30 days. Many Khavinson protocols use Cardiogen first, then Chelohart for the longer follow-up course.
Should I always take Ventfort with Chelohart?
Yes — Vita-Stream and Khavinson both recommend it. Heart health depends on both the muscle (Chelohart) and the vascular delivery system (Ventfort). Using them together provides comprehensive cardiovascular organ system support.

References

  1. Khavinson VKh et al. "Effect of peptide preparations on the aging cardiovascular system".” Advances in Gerontology (2004). PMID: 15570776

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Recommended SourceOral Bioregulator

Get Chelohart from Vita-Stream — the comprehensive distributor for authentic Khavinson bioregulators. Oral capsules, no injections required.

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