Chelohart
Heart Extract Bioregulator · Cardiac Cytomax · Челохарт
Chelohart is the Cytomax myocardial complex. Cardiogen is the heart cytogen. Ventfort is vessels. Do not treat “cardio” as one peptide.
Use-case scores
0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.
- Longevity / aging3.5/10
Khavinson-school tissue peptide. Single-lab concentration after haircut. Not a Western Phase 3 geroprotector.
Compound card
- Sequence
- Heart muscle peptide complex (mixture, not a single CAS)
- Class
- Khavinson Cytomax capsule complex (Heart muscle)
- Formula
- Polypeptide extract (Myocardium tissue <10 kDa)
- Status
- Not FDA-approved · research use
How it works
Chelohart (A-14) is a Cytomax natural polypeptide extract from the cardiac muscle (myocardium) of young calves, delivering a broad-spectrum library of short peptide signals (<10 kDa) targeting human cardiomyocytes. The heart is the most metabolically active organ in the body - by age 60, cardiac output and cardiomyocyte regenerative capacity have measurably declined, leaving the heart more vulnerable to ischemia, oxidative damage, and arrhythmia.
Chelohart's peptides penetrate cardiomyocyte nuclei to relax age-silenced chromatin and reactivate transcription of proteins critical to heart muscle integrity: sarcomere proteins (actin, myosin), mitochondrial respiratory enzymes, and antioxidant defense genes (SOD, catalase). This distinguishes it sharply from simply "protecting" the heart with antioxidants - it works at the gene regulation level.
In the Khavinson system, Chelohart is the natural oral extract counterpart to Cardiogen (the synthesized tetrapeptide Ala-Glu-Asp-Arg). Khavinson's published research from the St. Petersburg Institute (2004) documents normalization of lipid metabolism, improved tolerance to physical load, and reduced cardiac stress markers in elderly patients following polypeptide bioregulator courses. The recommended companion is always Ventfort (A-3, blood vessel extract) to simultaneously support the vascular delivery system alongside the cardiac muscle.
Source: PMID: 15677927
Khavinson map
Canonical 41Used in bioregulator stacks
Manufacturer-style organ combinations - not FDA protocols. Every name is a live leaf.
The Khavinson school
Vladimir Khatskelevich Khavinson (1946–2024) spent five decades at what became the St. Petersburg Institute of Bioregulation and Gerontology arguing a simple, stubborn idea: aging is, in part, a failure of tissue-specific peptide signals, and those signals can be restored. The first products were not “peptides” in the Instagram sense. They were Cytamins - polypeptide fractions isolated from a named organ of young animals. Later commercial refinements of those fractions are sold as Cytomaxes (Cytomed / NPCRIZ): still mixtures, still oral capsules, still defined by the source organ rather than a single sequence. When the group identified short active motifs inside those mixtures, they synthesized them as Cytogens - di-, tri-, and tetrapeptides with a one-letter code (KE, AEDG, KED, EDR, KEDP, and so on).
That three-layer stack is the whole map. Cytamin / pharmaceutical extracts (Thymalin, Epithalamin, Cortexin, Retinalamin, Prostatilen) are the clinic-era injectables registered in the former Soviet pharmacopeia. Cytomaxes are the capsule complexes Cytomed still lists as a 21-SKU organ line. Cytogens are the defined synthetics. English-language educators, including Brenden Henry’s public writing at Peptide Science Institute, add a further commercial distinction - later analog SKUs (N-acetyl, amidate, “V2” complexes) sold as more stable or more diverse than the original Cytomed lots. That last layer is a product taxonomy, not a Khavinson paper. We describe it so readers are not gaslit by three bottles with the same organ name. We do not reproduce paid Peptide Mastery protocols, Precision Cell Method language, or anyone else’s course IP.
Full Cytamin → Cytomax → Cytogen map, literature limits, and how we counted 41
The mechanism Khavinson published is epigenetic, not receptor-agonist in the GLP-1 sense. Short peptides are claimed to enter nuclei, interact with DNA/histones, and reopen tissue-specific transcription that condensed with age (heterochromatin → euchromatin). Reviews in the Bulletin of Experimental Biology and Medicine and Neuroendocrinology Letters (PMID 14523363, 15677927, 23888677) are the citable core. Complementary GI pharmacology is not mystical: di- and tripeptides are PEPT1/LAT substrates, which is why oral capsules are even a conversation. What is not established in Western Phase 3 programs is organ-by-organ disease treatment, telomere reversal as a clinical endpoint, or the manufacturer claim that Cytomax is “a third stronger” than Cytogen. Those are NPCRIZ marketing sentences.
Khavinson’s group published hundreds of papers, many in Russian, many in the same journal family. That is a real literature. It is also a literature with limited independent Western replication, small n, and a habit of using one review PMID as a stamp on every organ. On this site a leaf earns its organ story, its Cytomax↔Cytogen pair, its sequence if it has one, and an honest sentence about what has not been shown. Reconstitution math belongs on cytogens sold as vials. Cytomax capsules do not get a fake 5 mg vial.
The 41 we treat as canonical are the 21 Cytomaxes on the public e-peptide/Cytomed list, the 12 Cytogens on that same commercial line (including Vesilut, which Western catalogs often drop), plus eight historically load-bearing molecules that sit beside the capsule SKUs: Epitalon, Vilon, Thymogen, Livagen, Cortagen, Prostamax, Thymalin, and Epithalamin. Honluten, Cortexin, Retinalamin, Prostatilen, Thymulin, N-acetyl-epitalon-amidate, Pinalex, and the GPL Man / GPL Femme kits are covered as adjacent - same school or same storefront, not padded into a fake 41.
Public English-language teaching (including Brenden Henry at peptidescienceinstitute.com) is cited as context, not copied. Paid Peptide Mastery / Peptide Salvation text stays theirs.
History of this molecule
Cardiomyocyte identity versus endothelial identity is the whole point of having two aisles. Khavinson’s heart line is muscle cells; the vessel line is the lining. Chelohart + Cardiogen is myocardium. Ventfort + Vesugen is vasculature. SS-31 is a mitochondrial cardiolipin peptide from a completely different American program (Szeto) - do not steal elamipretide papers.
Heart failure remains GDMT. A capsule is not carvedilol.
Caveats
Heart Cytomax is not a US dietary-supplement monograph and not a drug. The tissue-extract model means lot-to-lot composition is a fingerprint, not a single CAS number. English-language “V2” bottles that claim more peptide diversity are a later commercial layer (mass-spec marketing from specific brands) - they are not Khavinson’s 1990s papers. Animal-source capsules are inappropriate if the reader has a religious or allergy constraint on the source species. None of this replaces care for the actual organ disease.
Full 41-map: Khavinson bioregulators index · Bioregulator stacks
Research Use Cases
- ✓Cardiac Cytomax vs Cardiogen
- ✓Not a cardiovascular treatment page
Dosing
| Phase | Dose | Frequency | Notes |
|---|---|---|---|
| Mini-Course / General Preventive (1 box) | 2 capsules (20 mg) | Once daily for 10 days, 30 min before meals | Standard Khavinson mini-course (1 pack / 20 caps). Repeat every 6 months. Always pair with Ventfort (A-3, vascular extract) - the heart and vessel health must be addressed together. |
| Full Monthly Course (ages 40–50) | 2 capsules (20 mg) | Twice daily for 30 days (120 caps = 2× 60-cap boxes) | Bi-annual 30-day courses from age 40–45; 3 courses/year after 50. Core cardiovascular stack: Chelohart (A-14) + Ventfort (A-3) + Endoluten (A-8) for cardio-neuroendocrine support. |
| Intensive / Cardiac Support Protocol | 2 capsules (20 mg) | Twice daily, repeated monthly as needed | For post-MI recovery, chronic heart failure support, or significant age-related cardiac decline. Physician supervision required. Consider adding Cardiogen (synthesized tetrapeptide) as an initial 10-day burst before transitioning to oral Chelohart maintenance. Max: 4 caps/day (40 mg). |
Administration
Chelohart: Not a research vial vs Oral capsule
- The defined-sequence vial in this aisle is the cytogen pair (Cardiogen (heart cytogen)), a different SKU.
- There is no pharmaceutical-extract SKU that is this capsule in a syringe.
- Reconstitute Cardiogen if you bought the heart cytogen. A Chelohart cake is a mis-ID. Do not steal Szeto tetrapeptide papers.
- Chelohart is an oral capsule complex. It is not a 5 mg lyophilized research vial.
- Inventing recon math for a zero-mg Cytomax vial is how people inject the wrong product.
- Not an official Cytomed sublingual tablet, IM ampoule, or eye drop either.
- Official form for Chelohart: swallow the capsule with water. No reconstitution step and no 5 mg cake.
- Heart-muscle Cytomax (Cytomed A-14). Ventfort / Vesugen are vessels, not myocardium. Not SS-31 / elamipretide.
- Course-based (10–30 days, a few times a year in manufacturer folklore), not a daily forever drug.
- Myocardium Cytomax is a peptide mixture / lot fingerprint, not a single CAS. English “V2” bottles are a later commercial layer, not a Khavinson RCT.
- Russian school literature is not an FDA organ-disease label.
- Third-party lingual SKUs exist in the wild. We do not claim sublingual as the official Cytomed Cytomax form.
Timeline
Who it is for
Cardiac Aging / Heart Muscle Health
LowBroad-spectrum myocardial bioregulator targeting cardiomyocyte gene expression. Best for preventive maintenance and post-illness recovery.
Cardiovascular Longevity Protocol
LowEssential component of the Khavinson cardiovascular stack alongside Ventfort (A-3). Addresses the cardiac muscle directly while Ventfort targets the vessel walls.
Safety & Considerations
Natural glandular extract (Cytomax) from bovine cardiac muscle, <10 kDa. No hormones. Meets strict European/Russian veterinary standards. Generally recognized as safe for long-term use.
Regulatory & Legal Status
Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.
Research Chemical
US Compounding: Not eligible / not available
⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.
Limits of current evidence
- Cytomax SKUs are oral capsules. Do not run SubQ reconstitution math on a zero-mg vial.
- Lot-to-lot composition is a fingerprint, not one sequence.
- This site will not treat the named organ disease from a peptide page.
- English-language V2 / analog bottles are a later commercial layer, not a Khavinson RCT.
Verdict
Chelohart is a Cytomax capsule complex from Heart muscle. It is not the paired cytogen, not a 5 mg research cake, and not a US supplement monograph. The organ story is in the dossier on this page.
Interactions & Contraindications
Standard Cytomax capsule identity, not a cardiology label.
Synergies & Common Stacks
Complex vs sequence. Capsules skip vial math.
Frequently Asked Questions
Oral capsule or injection?▼
Chelohart vs Cardiogen vs Ventfort?▼
Is this SS-31?▼
MI treatment?▼
Reconstitution?▼
Should I take Chelohart or Cardiogen?▼
Should I always take Ventfort with Chelohart?▼
References
- Khavinson VKh et al. “Tissue-specific effects of peptides.” Bulletin of Experimental Biology and Medicine (2005). PMID: 15677927
- Khavinson VKh, Lin’kova NS, Tarnovskaya SI “Short peptides regulate gene expression.” Bulletin of Experimental Biology and Medicine (2013). PMID: 23888677
- Khavinson VKh, Morozov VG “Peptide regulation of aging: from experimental studies to clinical practice.” Advances in Gerontology (2003). PMID: 14523363
- Khavinson VKh et al. “"Effect of peptide preparations on the aging cardiovascular system".” Advances in Gerontology (2004). PMID: 15570776
📚 Related Articles
Get Chelohart from Vita-Stream - a distributor for Khavinson-line oral capsules. No reconstitution math on a Cytomax bottle.
Affiliate link · Full review