Glandokort
Glandokort is a deeply potent Cytomax natural peptide bioregulator extracted directly from youthful adrenal tissue. It serves as the ultimate biological intervention for catastrophic "adrenal fatigue" and severe chronic stress exposure. By aggressively stabilizing the Hypothalamic-Pituitary-Adrenal (HPA) axis, it is heavily favored by elite operators and executives to recover from massive burnout, violently normalizing cortisol resistance and restoring deep systemic energy reserves.
Quick Stats
Scientific Data
Mechanism of Action
Glandokort (A-17) is a Cytomax natural polypeptide extract from the adrenal glands of young calves, targeting the human adrenal cortex to restore the regulatory gene expression responsible for cortisol rhythm, DHEA production, and stress adaptation. The adrenal glands are the body's primary stress response organs: the cortex produces glucocorticoids (cortisol), mineralocorticoids (aldosterone), and androgens (DHEA), while the medulla releases adrenaline. Chronic stress, poor sleep, illness, or simply the passage of time causes progressive adrenal functional decline — commonly called "adrenal fatigue," though more precisely described as HPA-axis (hypothalamic-pituitary-adrenal) dysregulation.
Glandokort delivers short peptide signals (<10 kDa) extracted from bovine adrenal tissue. Unlike adaptogenic herbs (ashwagandha, rhodiola) that modulate cortisol receptors or stress signaling pathways, Glandokort works upstream: it relaxes age-silenced chromatin in adrenal cortex cells to reactivate the genes encoding steroidogenesis enzymes (StAR, CYP11A1, CYP21A2) and ACTH receptor density. This restores the adrenal gland's intrinsic capacity to mount an appropriate cortisol response rather than chronically over- or under-producing.
In the Khavinson longevity system, Glandokort is paired with Endoluten (A-8, pineal/melatonin) to address the full HPA axis reset — since the pineal gland sets the circadian master rhythm that determines the daily cortisol awakening response. Together they address both the upstream circadian control and the downstream adrenal output capacity.
Source: PMID: 15677927
Background & History
Glandokort is the adrenal gland Cytomax extract, supporting HPA axis normalization.
Research Use Cases
- ✓Adrenal function
- ✓Stress resilience
- ✓Cortisol/DHEA balance
Dosing Protocol
| Typical Dose | 1-2 capsules/day |
| Frequency | 1-2× daily for 10-30 day cycles |
| Half-Life | ~30 minutes (estimated) |
Dosing Protocols
Mini-Course / General Preventive (1 box)
Full Monthly Course (Burnout / Stress Recovery)
Intensive / HPA Axis Restoration Protocol
Administration
Expected Timeline
Who Is It For?
Adrenal Fatigue / HPA-Axis Dysregulation
LowTargets adrenal cortex gene expression. Restores steroidogenesis enzyme activity rather than providing exogenous hormone stimulation.
Chronic Stress / Burnout Recovery
LowWorks upstream of adaptogens by restoring adrenal cellular capacity. Best combined with Endoluten (A-8) for the full HPA-axis reset.
Safety & Considerations
Natural glandular extract (Cytomax) from bovine adrenal tissue, <10 kDa. Does not contain cortisol or active steroid hormones. Meets European/Russian veterinary standards. Generally recognized as safe.
Regulatory & Legal Status
Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.
Research Chemical
US Compounding: Not eligible / not available
⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.
Interactions & Contraindications
Caution in Cushing syndrome. Monitor cortisol.
Dosing Quick Reference
Frequently Asked Questions
Does Glandokort contain cortisol?▼
What is the best stack for burnout recovery?▼
References
- Khavinson VKh “"Peptide bioregulators — a new class of geroprotectors".” Bulletin of Experimental Biology and Medicine (2002). PMID: 12677266
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Get Glandokort from Vita-Stream — the comprehensive distributor for authentic Khavinson bioregulators. Oral capsules, no injections required.
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