CalcMyPeptide
Khavinson BioregulatorAlso known as: Muscle Extract Bioregulator, Skeletal Muscle Cytomax

Gotratix

Gotratix is a specialized Cytomax natural peptide fraction formulated explicitly from the triceps of young animals to target absolute skeletal muscle regeneration. Standing apart from traditional anabolic pathways, it is leveraged by elite strength athletes and anti-aging physicians alike to aggressively combat age-related sarcopenia (muscle wasting), radically accelerate recovery between brutal training sessions, and forcefully sustain high-output muscle protein synthesis.

Reviewed by CalcMyPeptide Editorial Team
Last updated: April 2026Evidence: Low

Quick Stats

Half-LifeMixture (variable)
Dose Range1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Vial SizesN/A (oral)
BioavailabilityOral capsules
Year Developed1980s

Scientific Data

Molecular Formula
Polypeptide extract (Skeletal muscle tissue <10 kDa)
Molecular Weight
Mixture (<10 kDa)
PubChem ID

Mechanism of Action

Gotratix (A-18) is a Cytomax natural polypeptide extract from the skeletal muscle tissue of young calves, delivering targeted peptide signals to human myocytes (muscle cells) to restore age-silenced gene expression controlling muscle protein synthesis, mitochondrial efficiency, and satellite cell (muscle stem cell) activation. Sarcopenia — the progressive, age-related loss of skeletal muscle mass and strength — begins as early as age 30 and accelerates dramatically after 50, with an estimated 3–8% decline per decade becoming 15% per decade after age 70.

The conventional counter-strategy is resistance training and protein intake, which work through IGF-1 and mTOR-mediated anabolic signaling. Gotratix operates at a more foundational level: it delivers epigenetic signals directly to myocyte nuclei to reactivate transcription of genes encoding myosin heavy chain isoforms, sarcomeric actin, mitochondrial biogenesis factors (PGC-1α), and satellite cell proliferation regulators. This is not a hormonal or pharmacological intervention — it is an epigenetic restoration of what the muscle cell's own gene program once expressed in youth.

Gotratix is used extensively by aging athletes, both to maintain performance and to accelerate recovery from training. In Khavinson's clinical protocols, it is most commonly paired with Bonomarlot (A-20, bone marrow) to address both muscle and blood cell regenerative capacity, and with Sigumir (A-4, cartilage/joints) for a complete locomotor system protocol.

Source: PMID: 15677927

Background & History

Gotratix is the skeletal muscle Cytomax extract, supporting myocyte function and sarcopenia prevention.

Research Use Cases

  • Muscle health
  • Sarcopenia prevention
  • Recovery support

Dosing Protocol

Typical Dose1-2 capsules/day
Frequency1-2× daily for 10-30 day cycles
Half-Life~30 minutes (estimated)

Dosing Protocols

Mini-Course / General Preventive (1 box)

Dose
2 capsules (20 mg)
Frequency
Once daily for 10 days, 30 min before meals
Note: Standard Khavinson mini-course (20 caps). Repeat every 6 months. Best combined with consistent resistance training for synergistic effect. Take in the morning or 30 min before primary training session.

Full Monthly Course (Anti-Sarcopenia / Performance)

Dose
2 capsules (20 mg)
Frequency
Twice daily for 30 days (120 caps = 2× 60-cap boxes)
Note: Bi-annual 30-day courses for adults experiencing measurable muscle loss or athletes over 40. Core sarcopenia stack: Gotratix (A-18) + Sigumir (A-4, joints) + Bonomarlot (A-20, bone marrow) for complete locomotor system protocol.

Intensive / Muscle Recovery Protocol

Dose
2 capsules (20 mg)
Frequency
Twice daily, repeated monthly
Note: Post-injury rehabilitation, rapid strength decline after illness/surgery, or progressive sarcopenia. Max: 4 caps/day (40 mg). Physician guidance for clinical use cases.

Administration

Route
Oral capsules (20-cap and 60-cap boxes)
Timing
Morning or pre-workout, 30 minutes before meals.
Fasting Required?
Yes — inject on an empty stomach

Expected Timeline

Days 1–14
Myocyte gene expression restoration initiated. Post-workout soreness may reduce earlier than usual.
Month 1–2
Improved recovery speed from training loads. Maintenance of muscle mass during periods of reduced physical activity.
Month 3–6
Measurable preservation of lean muscle mass. Improved mitochondrial efficiency in trained muscle groups.

Who Is It For?

Sarcopenia Prevention (Ages 40+)

Low

Restores myocyte gene expression for myosin heavy chain isoforms and satellite cell proliferation — the upstream drivers of age-related muscle loss.

Athletic Recovery / Sports Performance

Low

Used by aging athletes for faster recovery and preservation of training adaptations. Works at the gene level, not receptor/hormone level.

Safety & Considerations

Natural glandular extract (Cytomax) from bovine skeletal muscle, <10 kDa. No anabolic hormones. Not a banned substance. Meets European/Russian veterinary standards. Generally recognized as safe.

Regulatory & Legal Status

FDA Status (US)
Research Only
WADA Status (2026)
Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change — verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Interactions & Contraindications

Standard Cytomax capsule protocol.

Dosing Quick Reference

Gotratix— Dosing Guide
Dose Range
1-2 capsules/day
Half-Life
~30 minutes (estimated)
Frequency
1-2× daily for 10-30 day cycles
Route
Oral
Khavinson Bioregulatorcalcmypeptide.com

Frequently Asked Questions

Is Gotratix like growth hormone or steroids?
No. Gotratix contains peptide signals (<10 kDa) from bovine skeletal muscle, completely free of hormones. It does not stimulate HGH or testosterone receptors. It works by restoring the gene expression program in your own myocytes — more like epigenetic reprogramming than pharmacological doping.
What is the best stack for muscle health?
The Khavinson locomotor system protocol combines Gotratix (A-18, muscle) + Sigumir (A-4, cartilage/joints) + Bonomarlot (A-20, bone marrow). This addresses muscle protein synthesis, joint structural integrity, and blood cell regeneration — the full musculoskeletal system.

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Recommended SourceOral Bioregulator

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