PT-141 Online: What Vyleesi and Compounded Bremelanotide Cost
PT-141 is bremelanotide. The FDA-approved version, Vyleesi, is for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD), and its maker says most commercially insured patients pay $0 for a 4-dose box, or $99 without coverage. Telehealth clinics also sell compounded bremelanotide, which is not FDA-approved, for $136 to $170 a month. Here is every price we found, cheapest first.
By CalcMyPeptide Editorial · Published · Prices checked · How we rank
Prices checked · Written by the CalcMyPeptide editorial team · Medical review pending
Quick answer
- Cheapest FDA-approved route: Vyleesi through its BlinkRx pharmacy. Cosette says most commercially insured patients pay $0 for a 4-dose box; without coverage the 4-dose box is $99. Government-insured patients are excluded from the savings program.
- Compounded bremelanotide online: HealthRX, $136/mo on a 12-month plan up to $170 month-to-month, provider visit and supplies included; not FDA-approved.
- Low desire is not the same problem as erections. For erectile dysfunction, generic sildenafil or tadalafil costs about $6–$7 for 30 tablets; see our ED cost page.
PT-141 (bremelanotide) prices, cheapest first
| Seller | Product | Price | Status | Includes |
|---|---|---|---|---|
| Vyleesi (Cosette) via BlinkRx | Vyleesi autoinjector, 4-dose boxLabel limits: no more than 1 dose in 24 hours or 8 doses a month. Copay help applies to 2 fills every 30 days. | $0 with commercial coverage (most patients); $99 without coverageseller's list price | FDA-approved brand | Medication shipped free by BlinkRx; prescription required (your clinician or Vyleesi’s third-party telehealth partner) |
| HealthRX | PT-141 (bremelanotide), compoundedVyleesi is the separately FDA-approved bremelanotide product, for premenopausal women with acquired, generalized HSDD. | $136/mo (12-month), $145 (6-month), $153 (3-month), $170 (monthly)source | Compounded (not FDA-approved) | Medication and supplies, provider visit, follow-ups, free shipping |
Sorted by the lowest published monthly cost. "Starting at" prices can change after a clinician sets your dose. Linked brands are affiliate or applied-for programs (rel="sponsored"); other sellers are listed as plain text for price context only.
How to pay the least
- If you are a premenopausal woman with an HSDD diagnosis and commercial insurance, ask your clinician to send a Vyleesi prescription to BlinkRx; Cosette says most commercially insured patients pay $0.
- No coverage: the 4-dose Vyleesi box is $99, which is less than a month of compounded bremelanotide at HealthRX ($136–$170) if you use 4 doses or fewer.
- Compounded bremelanotide is the only route for uses outside Vyleesi’s label (for example men). The trials behind Vyleesi studied the approved product in premenopausal women, not compounded versions or other groups.
What the evidence shows
Two identical 24-week phase 3 trials (RECONNECT, 1,247 premenopausal women with HSDD) found bremelanotide improved desire and reduced distress about low desire compared with placebo (Kingsberg et al., Obstet Gynecol 2019). A 52-week open-label extension found no new safety signals; nausea was the most common side effect (Simon et al., Obstet Gynecol 2019). Individual results vary.
CoreAge Rx “4Play” is not PT-141
CoreAge Rx’s 4Play is a compounded erectile dysfunction suspension (apomorphine, sildenafil, tadalafil and vardenafil) starting at $114 for 5 bottles. It does not contain bremelanotide, so we do not list it as a PT-141 option.
FAQ
How much does PT-141 cost?
Vyleesi, the FDA-approved bremelanotide, is $0 for most commercially insured patients or $99 per 4-dose box without coverage, per its maker. Compounded bremelanotide from HealthRX is $136 to $170 a month depending on plan length (checked Oct 7, 2026).
Is PT-141 the same as Vyleesi?
Vyleesi is the FDA-approved bremelanotide autoinjector for premenopausal women with acquired, generalized HSDD. “PT-141” sold by telehealth clinics is usually compounded bremelanotide, which is not FDA-approved and was not the product studied in the approval trials.
Can men get PT-141?
Vyleesi is not approved for men. Some telehealth clinics prescribe compounded bremelanotide off-label; whether that is appropriate is a decision for a licensed clinician.
Do I need a prescription for PT-141?
Yes. Both Vyleesi and compounded bremelanotide require a prescription in the US. Sellers offering PT-141 without one are selling unregulated “research” products.
Related
Sources
Prices and product facts come from each seller's own pages, read Oct 7, 2026. We link only to sellers we have an affiliate relationship with and to government and research sources; other sellers' prices are quoted as plain text.
- HealthRX: PT-141 (bremelanotide), compounded
- Kingsberg et al., Obstet Gynecol 2019: RECONNECT phase 3 trials (PMID 31599840)
- Simon et al., Obstet Gynecol 2019: 52-week safety extension (PMID 31599847)
- CoreAge Rx: 4Play (ED suspension, not bremelanotide)
- FDA: Compounding questions and answers
Also read for prices (not linked; no affiliate relationship): vyleesi.com.