Prostatilen
Samprost · Vitaprost · Сампрост · Простатилен
Prostatilen (Vitaprost/Samprost) is the pharmaceutical prostate extract used in CIS urology. Adjacent to the 41. Libidon is Cytomax; Prostamax is KEDP.
Use-case scores
0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.
- Sexual / hormonal3/10
Russian extract literature. Not a US BPH drug. Not the KEDP tetrapeptide.
Compound card
- Class
- Bovine prostate polypeptide extract (Cytomax class; not Prostamax KEDP)
- Formula
- Polypeptide extract (Prostate tissue)
- Status
- Not FDA-approved · research use
How it works
Prostatilen is a pharmaceutical-grade polypeptide extract derived from the prostate glands of young bulls. Manufactured primarily in Russia and Eastern Europe, it is an injectable therapeutic containing water-soluble peptides with specific tropism (attraction) to the human prostate gland.
It acts by improving prostate microcirculation, reducing tissue edema (swelling), inhibiting leukocyte infiltration (inflammation), and normalizing the secretory function of prostate epithelial cells. It is a widely prescribed clinical treatment in Russia for chronic abacterial prostatitis and benign prostatic hyperplasia (BPH). It works via the same tissue-specific gene regulation pathways as the oral Cytomax version (Libidon), but at a higher, clinical-grade concentration.
Source: PMID: 15677927
Khavinson map
Adjacent (not padded into the 41)Used in bioregulator stacks
Manufacturer-style organ combinations - not FDA protocols. Every name is a live leaf.
The Khavinson school
Vladimir Khatskelevich Khavinson (1946–2024) spent five decades at what became the St. Petersburg Institute of Bioregulation and Gerontology arguing a simple, stubborn idea: aging is, in part, a failure of tissue-specific peptide signals, and those signals can be restored. The first products were not “peptides” in the Instagram sense. They were Cytamins - polypeptide fractions isolated from a named organ of young animals. Later commercial refinements of those fractions are sold as Cytomaxes (Cytomed / NPCRIZ): still mixtures, still oral capsules, still defined by the source organ rather than a single sequence. When the group identified short active motifs inside those mixtures, they synthesized them as Cytogens - di-, tri-, and tetrapeptides with a one-letter code (KE, AEDG, KED, EDR, KEDP, and so on).
That three-layer stack is the whole map. Cytamin / pharmaceutical extracts (Thymalin, Epithalamin, Cortexin, Retinalamin, Prostatilen) are the clinic-era injectables registered in the former Soviet pharmacopeia. Cytomaxes are the capsule complexes Cytomed still lists as a 21-SKU organ line. Cytogens are the defined synthetics. English-language educators, including Brenden Henry’s public writing at Peptide Science Institute, add a further commercial distinction - later analog SKUs (N-acetyl, amidate, “V2” complexes) sold as more stable or more diverse than the original Cytomed lots. That last layer is a product taxonomy, not a Khavinson paper. We describe it so readers are not gaslit by three bottles with the same organ name. We do not reproduce paid Peptide Mastery protocols, Precision Cell Method language, or anyone else’s course IP.
Full Cytamin → Cytomax → Cytogen map, literature limits, and how we counted 41
The mechanism Khavinson published is epigenetic, not receptor-agonist in the GLP-1 sense. Short peptides are claimed to enter nuclei, interact with DNA/histones, and reopen tissue-specific transcription that condensed with age (heterochromatin → euchromatin). Reviews in the Bulletin of Experimental Biology and Medicine and Neuroendocrinology Letters (PMID 14523363, 15677927, 23888677) are the citable core. Complementary GI pharmacology is not mystical: di- and tripeptides are PEPT1/LAT substrates, which is why oral capsules are even a conversation. What is not established in Western Phase 3 programs is organ-by-organ disease treatment, telomere reversal as a clinical endpoint, or the manufacturer claim that Cytomax is “a third stronger” than Cytogen. Those are NPCRIZ marketing sentences.
Khavinson’s group published hundreds of papers, many in Russian, many in the same journal family. That is a real literature. It is also a literature with limited independent Western replication, small n, and a habit of using one review PMID as a stamp on every organ. On this site a leaf earns its organ story, its Cytomax↔Cytogen pair, its sequence if it has one, and an honest sentence about what has not been shown. Reconstitution math belongs on cytogens sold as vials. Cytomax capsules do not get a fake 5 mg vial.
The 41 we treat as canonical are the 21 Cytomaxes on the public e-peptide/Cytomed list, the 12 Cytogens on that same commercial line (including Vesilut, which Western catalogs often drop), plus eight historically load-bearing molecules that sit beside the capsule SKUs: Epitalon, Vilon, Thymogen, Livagen, Cortagen, Prostamax, Thymalin, and Epithalamin. Honluten, Cortexin, Retinalamin, Prostatilen, Thymulin, N-acetyl-epitalon-amidate, Pinalex, and the GPL Man / GPL Femme kits are covered as adjacent - same school or same storefront, not padded into a fake 41.
Public English-language teaching (including Brenden Henry at peptidescienceinstitute.com) is cited as context, not copied. Paid Peptide Mastery / Peptide Salvation text stays theirs.
History of this molecule
Authorized extract product in its home market, rectal and injectable presentations in labeling folklore. That is a different object than a 10 mg KEDP research vial. We keep the triad honest.
Caveats
Extract. Rising PSA is a workup. Not FDA in the US as this named product for BPH in the American sense.
Full 41-map: Khavinson bioregulators index · Bioregulator stacks
Research Use Cases
- ✓Chronic abacterial prostatitis
- ✓Benign prostatic hyperplasia
- ✓Post-prostatectomy recovery
- ✓Male genitourinary aging
Dosing
| Phase | Dose | Frequency | Notes |
|---|---|---|---|
| Clinical Protocol | 5 - 10 mg | Daily IM injection for 5-10 days | Russian clinical standard for prostatitis. Often also available as a rectal suppository (Vitaprost). |
Administration
Prostatilen: CIS IM extract vs Rectal suppository
- Authorized extract product in its home market. Real triad with Libidon and Prostamax.
- IM is the injectable clinic route, not a 5 mg abdomen lifestyle chart.
- Food does not change an IM shot.
- Not a US BPH indication. Rising PSA is a workup.
- Not Vesilut / Chitomur (bladder). Catalogs that file Samprost under bladder are mixing the brand.
- Identity risk on gray-market powder.
- Rectal suppository is a real CIS presentation for this extract.
- Keeps Libidon (Cytomax swallow) separate from the extract.
- Not a sublingual tablet. Nobody manufactures this SKU that way.
- Suppository ≠ Prostamax KEDP capsule ≠ Libidon capsule.
- Not tadalafil. Not finasteride.
- Do not invent a swallowed-extract dose to look complete.
Timeline
Who it is for
Chronic Prostatitis / BPH
ModerateRegistered medicine in Russia for acute and chronic prostate inflammation.
Reconstitution
| Vial | Water | Concentration | Example dose |
|---|---|---|---|
| 5 mg lyophilized | 1 mL BAC | 5 mg/mL | Extract kits vs research cakes. Capsules skip the calculator. |
Change vial size or water volume? Open the reconstitution calculator.
Safety & Considerations
Registered pharmaceutical in Russia. Clinical trials show very low incidence of systemic side effects. Painful administration (IM injection) compared to oral Libidon.
Regulatory & Legal Status
Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.
Research Chemical
US Compounding: Not eligible / not available
⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.
Limits of current evidence
- PMID 15677927 is organ-map class, not an FDA BPH program.
- This site will not treat BPH or prostatitis from this page.
Verdict
Prostatilen is the prostate tissue extract. Prostamax is KEDP. Samprost/Vitaprost are brand collisions. Not finasteride.
Interactions & Contraindications
Standard Cytomax/injection protocol. No significant drug interactions reported in Russian clinical literature.
Synergies & Common Stacks
Prostate extract plus testicular cytogen in Khavinson practice. School pairing, not a male-reproductive NDA on this site.
Prostatilen + Libidon both target prostate health - Prostatilen from natural extract, Libidon from synthetic peptide approach.
Frequently Asked Questions
In the 41?▼
Vs Prostamax?▼
BPH?▼
Same as Libidon?▼
Is Samprost a bladder peptide?▼
IM, rectal, or capsule?▼
How does Prostatilen differ from Libidon?▼
Is Samprost a bladder bioregulator?▼
References
- Khavinson VKh et al. “Tissue-specific effects of peptides.” Bulletin of Experimental Biology and Medicine (2005). PMID: 15677927
- Al-Shukri SK et al. “"Efficacy of prostatilen in the treatment of chronic prostatitis".” Urologiia (2006). PMID: 16922119
Get Prostatilen from Vita-Stream - a distributor for Khavinson-line oral capsules. No reconstitution math on a Cytomax bottle.
Affiliate link · Full review