All ProtocolsIntermediate

Cognitive Enhancement Protocol

Neuro 3 Plus bioregulator triad (brain, vessels, liver) plus Semax/Selank, with Dihexa reserved for advanced users.

Duration

10-18 day nootropic cycles; 20-30 day bioregulator courses

First Results

Days for Semax/Selank; weeks for cytomax courses

Peptides in Stack

6

1Overview

A calmer focus window on Semax/Selank days and a slower "hardware" course from Cerluten + Ventfort + Svetinorm. Dihexa is experimental. We do not sell a Neuro 3 Plus bottle here; we map the three leaves.

Ideal Candidates

People who want a vascular + neuronal + hepatic base before chasing experimental nootropics
Users already familiar with Semax/Selank cycling
Advanced users considering Dihexa who understand preclinical risk

Contraindications

Uncontrolled psychiatric illness, active mania, or recent stimulant psychosis
Pregnancy
History of seizures without a neurologist in the loop (excitatory stacks)

2The Science

Atlas frames cognition as supply (Ventfort), tissue (Cerluten), and clearance (Svetinorm), then BDNF-leaning peptides (Semax), anxiolytic GABA/enkephalin tone (Selank), then growth-factor mimetics (Dihexa). That hierarchy is a useful teaching model. It is not a diagnosis, and it is not a license to run Dihexa continuously.


3Clinical Evidence

Emerging Evidence
12 human studies60 animal studies25 in vitro

Key Findings

1

Semax has Russian clinical use and BDNF-related mechanistic papers; Western RCTs for "biohacking IQ" do not exist at that marketing grade

2

Selank has anxiolytic literature in Russian populations; stacking with Semax is community practice

3

Dihexa synaptogenesis potency claims are preclinical, not a human cognitive indication

Study Limitations

  • Neuro 3 Plus is a vendor bundle name. We link the three peptides, not a SKU.
  • Citicoline, polygala, and 4-DMA-7,8-DHF are not in this library. We do not invent product pages for them.
  • Dihexa is not a beginner compound.

3The Peptide Stack

CE

Brain cytomax. The "Cerluten" leaf of the Neuro 3 triad.

Mechanism: CNS cytamine complex; oral capsules, empty stomach.

Half-life: ~30 minutes (estimated)Dose range: 1-2 capsules/day
VE

Cerebral perfusion support in the same triad.

Mechanism: Vascular cytomax; oral.

Half-life: ~30 minutes (estimated)Dose range: 1-2 capsules/day
SV

Hepatic cytomax. Atlas includes liver support so metabolic junk is not the silent variable.

Mechanism: Liver cytamine complex; oral.

Half-life: ~30 minutes (estimated)Dose range: 1-2 capsules/day
SE

ACTH(4-10) analog used for BDNF-leaning focus. Typical community: 10-18 days on, long off.

Mechanism: Intranasal or SubQ; not a daily forever nootropic.

Half-life: ~2-3 minutes (rapid metabolism)Dose range: 200-600 mcg/day (intranasal)
SE

Tuftsin analog for "calm focus" rather than stimulation.

Mechanism: Often stacked with Semax; same cycle discipline.

Half-life: ~3 minutes (rapid metabolism)Dose range: 250-750 mcg/day (intranasal)
DI

HGF/c-Met mimetic from Washington State work. Preclinical synaptogenesis claims. Advanced only.

Mechanism: Potent growth-factor signaling; theoretical proliferation risk. Short cycles if used at all.

Half-life: ~2-4 hours (estimated)Dose range: 10-40 mg/day (oral/intranasal)

4Protocol Tiers

Tier 1: Neuro 3 leaves

Cerluten + Ventfort + Svetinorm as swallowed capsules, empty stomach. This is the maintenance triad.

Duration
20-30 days
Frequency: Daily during the course
Cerluten1-2 capsules
Timing: Morning, empty stomach
Ventfort1-2 capsules
Timing: Morning, empty stomach
Svetinorm1-2 capsules
Timing: Morning, empty stomach

Tier 2: Semax + Selank

Acute nootropic block. Weekend washout of the synthetics is a common pattern; keep the cytomax course if you are mid-cycle.

Duration
10-18 days on, 8-12 weeks off
Frequency: Daily during the on-window, morning
Semax200-600 mcg
Timing: Morning
Selank200-400 mcg
Timing: Morning or split

Tier 3: Dihexa (experimental)

Advanced users only. Do not stack with other aggressive growth-factor mimetics without a physician who actually knows the compound.

Duration
4-6 weeks max
Frequency: Daily during a short cycle, then off
Dihexa8-20 mg (community oral/transdermal ranges)
Timing: Morning
Clinical Note: Preclinical. Short cycles. Not a homework drug.

5Lifestyle Integration

Peptides are one input in a larger system. Without these non-negotiable lifestyle factors, even the best protocol will underperform.

🏋️Training

Zone 2 plus some skill work. Cognition stacks do not replace sleep debt from night training.

🥗Nutrition

Protein and omega-3s for membranes. Choline sources if you run acetylcholine-heavy days. We do not stock Cognizin as a peptide leaf.

🌙Sleep

Selank is not a DSIP replacement. Protect the sleep window or Semax will feel like jitter.

🧘Stress Management

If the problem is burnout and dopamine flattening, the dopamine-reset protocol is the better first page.

6Timeline & Expectations

Days 1-7

What You'll NoticeSemax/Selank are the noticeable days. Cytomax is not a coffee.
What's Happening BiologicallyPeptide nootropics on board; vascular/brain courses just starting.

Days 10-18

What You'll NoticeTime to stop Semax/Selank if that was the plan. Do not chase tolerance.
What's Happening BiologicallyReceptor and BDNF pathways need an off-ramp.

Weeks 4-6

What You'll NoticeFinish the oral course. Reassess whether Dihexa was ever justified.
What's Happening BiologicallyMaintenance vs escalation. Most people should stay at Tier 1-2.

7Monitoring & Safety

Key Metrics to Track

Sleep and anxietyIf Semax wrecks sleep, cut dose or stop. Do not add more Selank as a cover.
Blood pressureVentfort is not an antihypertensive. Track BP if you already have vascular disease.

Troubleshooting

Wired but tired
Possible Causes
  • Semax too late in the day
  • Caffeine stacked on top
Solutions
  • Morning-only Semax
  • Cut caffeine 50% on cycle days
No subjective change on cytomax
Possible Causes
  • Wrong expectation
  • Course shorter than 3 weeks
Solutions
  • Judge cytomax over a full course, not day 2
  • Do not escalate to Dihexa to "feel something"

8Further Reading

Dive deeper into the individual peptides and methodologies behind this protocol.